Arformoterol

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Arformoterol
Arformoterol.svg
Arformoterol ball-and-stick model.png
Names
Trade namesBrovana
Other namesArformoterol tartrate
  • N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl) propan-2-yl]amino]ethyl] phenyl]formamide
Clinical data
Drug classLABA[1]
Main usesCOPD[1]
Side effectsDiarrhea, sinusitis, rash, peripheral swelling, chest pain[1]
Routes of
use
Inhalation solution for nebuliser
External links
AHFS/Drugs.comMonograph
US NLMArformoterol
MedlinePlusa602023
Legal
License data
Legal status
Pharmacokinetics
Protein binding52–65%
Elimination half-life26 hours
Chemical and physical data
FormulaC19H24N2O4
Molar mass344.411 g·mol−1
  • InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)/t13-,19+/m1/s1 checkY
  • Key:BPZSYCZIITTYBL-YJYMSZOUSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Arformoterol, sold under the brand name Brovana, is a medication used for the long-term treat chronic obstructive pulmonary disease (COPD).[1] It is not indicated for sudden worsening.[2] It is given by nebulization.[1] Maximum effect may take 3 hours.[1]

Common side effects include diarrhea, sinusitis, rash, peripheral swelling, and chest pain.[1] Other side effect ma include low potassium, anaphylaxis, and bronchospasm.[1] Safety in pregnancy is unclear.[1] It is a long-acting β2 adrenoreceptor agonist (LABA).[1] It is the active component of formoterol.[1]

Arformoterol was approved for medical use in the United States in 2006.[1] It is available as a generic medication.[3] In the United States a month of medication costs about 240 USD as of 2022.[3]

Medical uses

Dosage

It is typically used at a dose of 15 micrograms twice per day.[1]

References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 "Arformoterol Monograph for Professionals". Drugs.com. Retrieved 16 January 2022.
  2. "DailyMed - ARFORMOTEROL TARTRATE solution". dailymed.nlm.nih.gov. Retrieved 16 January 2022.
  3. 3.0 3.1 "Arformoterol Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 16 January 2022.

External links

External sites:
Identifiers: