Arformoterol

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Arformoterol
Arformoterol.svg
Arformoterol ball-and-stick model.png
Names
Trade namesBrovana
Other namesArformoterol tartrate
  • N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl) propan-2-yl]amino]ethyl] phenyl]formamide
Clinical data
Drug classLABA[1]
Main usesCOPD[1]
Side effectsDiarrhea, sinusitis, rash, peripheral swelling, chest pain[1]
Routes of
use
Inhalation solution for nebuliser
External links
AHFS/Drugs.comMonograph
US NLMArformoterol
MedlinePlusa602023
Legal
License data
Legal status
Pharmacokinetics
Protein binding52–65%
Elimination half-life26 hours
Chemical and physical data
FormulaC19H24N2O4
Molar mass344.411 g·mol−1
  • InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)/t13-,19+/m1/s1 checkY
  • Key:BPZSYCZIITTYBL-YJYMSZOUSA-N checkY

Arformoterol, sold under the brand name Brovana, is a medication used for the long-term treat chronic obstructive pulmonary disease (COPD).[1] It is not indicated for sudden worsening.[2] It is given by nebulization.[1] Maximum effect may take 3 hours.[1]

Common side effects include diarrhea, sinusitis, rash, peripheral swelling, and chest pain.[1] Other side effect ma include low potassium, anaphylaxis, and bronchospasm.[1] Safety in pregnancy is unclear.[1] It is a long-acting β2 adrenoreceptor agonist (LABA).[1] It is the active component of formoterol.[1]

Arformoterol was approved for medical use in the United States in 2006.[1] It is available as a generic medication.[3] In the United States a month of medication costs about 240 USD as of 2022.[3]

Medical uses

Dosage

It is typically used at a dose of 15 micrograms twice per day.[1]

References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 "Arformoterol Monograph for Professionals". Drugs.com. Archived from the original on 25 January 2021. Retrieved 16 January 2022.
  2. "DailyMed - ARFORMOTEROL TARTRATE solution". dailymed.nlm.nih.gov. Archived from the original on 16 January 2022. Retrieved 16 January 2022.
  3. 3.0 3.1 "Arformoterol Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 14 August 2016. Retrieved 16 January 2022.

External links

External sites:
Identifiers: