Guanabenz
Jump to navigation
Jump to search
This article needs additional citations for verification. (September 2014) |
![]() | |
![]() | |
Clinical data | |
---|---|
AHFS/Drugs.com | Consumer Drug Information |
MedlinePlus | a686003 |
ATC code |
|
Pharmacokinetic data | |
Protein binding | 90% |
Elimination half-life | 6 hours |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
IUPHAR/BPS | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.023.410 |
Chemical and physical data | |
Formula | C8H8Cl2N4 |
Molar mass | 231.08 g·mol−1 |
3D model (JSmol) | |
| |
| |
(verify) |
Guanabenz (pronounced GWAHN-a-benz, sold under the trade name Wytensin) is an alpha agonist of the alpha-2 adrenergic receptor that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension).[1][2]
The most common side effects during guanabenz therapy are dizziness, drowsiness, dry mouth, headache and weakness.
Guanabenz can make one drowsy or less alert, therefore driving or operating dangerous machinery is not recommended.
See also
References
- ^ Walker BR, Hare LE, Deitch MW (1982). "Comparative antihypertensive effects of guanabenz and clonidine". The Journal of International Medical Research. 10 (1): 6–14. doi:10.1177/030006058201000102. PMID 7037502. S2CID 2139809.[permanent dead link]
- ^ Bonham AC, Trapani AJ, Portis LR, Brody MJ (1984). "Studies on the mechanism of the central antihypertensive effect of guanabenz and clonidine". Journal of Hypertension Supplement. 2 (3): S543-6. PMID 6599714.[permanent dead link]
Categories:
- All articles with dead external links
- Articles with dead external links from January 2020
- Articles with permanently dead external links
- Articles with short description
- Short description matches Wikidata
- Articles needing additional references from September 2014
- All articles needing additional references
- Drugs not assigned an ATC code
- ECHA InfoCard ID from Wikidata
- Drugs with no legal status
- Drugboxes which contain changes to watched fields
- Alpha-2 adrenergic receptor agonists
- Chloroarenes
- Guanidines
- All stub articles
- Antihypertensive agent stubs