|Trade names||Alvesco, Omnaris, Omniair, others|
|Other names||(11β, 16α)-16, 17-[[(R)-cyclohexylmethylene]bis(oxy)]-11-hydroxy-21- (2-methyl-1-oxopropoxy)- pregna-1, 4-diene-3, 20-dione|
|Main uses||Asthma, allergic rhinitis|
|Side effects||Inhaled: Headache, throat pain, upper respiratory infection, join pain, thrush, pneumonia|
Nose spray: Nosebleeding, headache, ear pain, throat pain
|Inhalation, nose spray|
|Typical dose||80 to 320 ucg OD to BID|
|Chemical and physical data|
|Molar mass||540.697 g·mol−1|
|3D model (JSmol)|
Ciclesonide, sold under the brand name Omnaris among others, is a medication used to treat asthma and allergic rhinitis. For asthma it is inhaled while for rhinitis it is used as a nose spray.
Common side effects when inhaled include headache, throat pain, upper respiratory infection, join pain, thrush, and pneumonia. Common side effects when sprayed in the nose include nosebleeding, headache, ear pain, and throat pain. Other side effects may include glaucoma and adrenal suppression. Safety in pregnancy has not been well studied. It is a corticosteroid, specifically a glucocorticoid.
Ciclesonide was patented in 1990 and approved for medical use in 2005. It was approved for use in the United States in 2006. In the United Kingdom 120 doses of 160 microgram inhaler costs the NHS about £38 as of 2021. This amount in the United States costs about 260 USD.
The dose for asthma is generally 80 to 320 micrograms once to twice per day.
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