Domesticine

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Domesticine
domesticine 2D skeletal
domesticine 3D BS
Names
Preferred IUPAC name
(6aS)-2-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H,10H-benzo[de][1,3]benzodioxolo[5,6-g]quinolin-1-ol
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C19H19NO4/c1-20-4-3-10-6-16(22-2)19(21)18-12-8-15-14(23-9-24-15)7-11(12)5-13(20)17(10)18/h6-8,13,21H,3-5,9H2,1-2H3/t13-/m0/s1
    Key: ZMNSHBTYBQNBPV-ZDUSSCGKSA-N
  • CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC5=C(C=C43)OCO5)O)OC
Properties
C19H19NO4
Molar mass 325.364 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Domesticine is an α1D-adrenergic receptor antagonist.[1]

References

  1. ^ Indra, B; Matsunaga, K; Hoshino, O; Suzuki, M; Ogasawara, H; Muramatsu, I; Taniguchi, T; Ohizumi, Y (2002). "(+/-)-Domesticine, a novel and selective alpha1D-adrenoceptor antagonist in animal tissues and human alpha 1-adrenoceptors". European Journal of Pharmacology. 445 (1–2): 21–9. doi:10.1016/s0014-2999(02)01601-1. PMID 12065190.