Diprafenone

From WikiProjectMed
Jump to navigation Jump to search
Diprafenone
Diprafenone.svg
Names
IUPAC name
1-[2-[2-Hydroxy-3-(2-methylbutan-2-ylamino)propoxy]phenyl]-3-phenylpropan-1-one
Identifiers
3D model (JSmol)
ChemSpider
MeSH C037836
UNII
  • InChI=1S/C23H31NO3/c1-4-23(2,3)24-16-19(25)17-27-22-13-9-8-12-20(22)21(26)15-14-18-10-6-5-7-11-18/h5-13,19,24-25H,4,14-17H2,1-3H3
    Key: VDKMYSMWQCFYBQ-UHFFFAOYSA-N
  • InChI=1/C23H31NO3/c1-4-23(2,3)24-16-19(25)17-27-22-13-9-8-12-20(22)21(26)15-14-18-10-6-5-7-11-18/h5-13,19,24-25H,4,14-17H2,1-3H3
    Key: VDKMYSMWQCFYBQ-UHFFFAOYAV
  • CCC(C)(C)NCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O
Properties
C23H31NO3
Molar mass 369.505 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Diprafenone is an antiarrhythmic beta adrenergic antagonist.[1]

References

  1. ^ Koytchev, R; Alken, RG; Mayer, O; Smith, I; Greenwood, M (1996). "Influence of food on the bioavailability and some pharmacokinetic parameters of diprafenone--a novel antiarrhythmic agent". European Journal of Clinical Pharmacology. 50 (4): 315–9. doi:10.1007/s002280050115. PMID 8803526.