Barnidipine
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Clinical data | |
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AHFS/Drugs.com | International Drug Names |
Routes of administration | Oral |
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Chemical and physical data | |
Formula | C27H29N3O6 |
Molar mass | 491.544 g·mol−1 |
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Barnidipine (INN; also known as mepirodipine) is a calcium channel blocker which belongs to the dihydropyridine (DHP) group of calcium channel blockers. It is used in the treatment of hypertension.[1]
Pharmacodynamics
Barnidipine is a pure S,S isomer, a lipophilic 1,4-dihydropyridine calcium channel blocker, which, like other compounds in the class, shows a high affinity for calcium channels, particularly the L-type slow channels of smooth muscle cells found in the vessel wall.[2] Calcium channel blocking drugs have the characteristic of interfering with the flow of calcium ions into the interior of cells through the slow channels of the plasma membrane.
References
Categories:
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