Clentiazem
Jump to navigation
Jump to search
Names | |
---|---|
Preferred IUPAC name
(2S,3S)-8-Chloro-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate | |
Identifiers | |
3D model (JSmol)
|
|
ChemSpider | |
PubChem CID
|
|
UNII | |
| |
| |
Properties | |
C22H25ClN2O4S | |
Molar mass | 448.9629 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
Clentiazem is a calcium channel blocker.[1]
It is a chlorine derivative of diltiazem.[2]
References
- ^ Giasson S, Garceau D, Homsy W, Dumont L (October 1995). "Pharmacodynamics and pharmacokinetics of clentiazem and diltiazem in closed-chest anesthetized dogs". Cardiovasc Drugs Ther. 9 (5): 685–92. doi:10.1007/BF00878551. PMID 8573551. S2CID 37503776.
- ^ Dagenais F, Hollmann C, Buluran J, Cartier R (October 1995). "Clentiazem and diltiazem preserve endothelium-dependent relaxation following global rat heart ischemia". Can J Cardiol. 11 (9): 816–22. PMID 7585280.
Categories:
- Articles without EBI source
- Articles without KEGG source
- Articles with changed ChemSpider identifier
- Articles with changed InChI identifier
- Articles containing unverified chemical infoboxes
- Articles with short description
- Short description matches Wikidata
- Calcium channel blockers
- Benzothiazoles
- Lactams
- Chloroarenes
- Acetate esters