MPMI (drug)

MPMI
Identifiers
	IUPAC name 3-[(1-methylpyrrolidin-2-yl)methyl]-1H-indole;
CAS Number	143321-54-4 ; 143322-55-8 (R enantiomer);
PubChem CID	53870442;
ChemSpider	68007055;
Chemical and physical data
Formula	C14H18N2
Molar mass	214.312 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1CCCC1CC2=CNC3=CC=CC=C32;
	InChI InChI=1S/C14H18N2/c1-16-8-4-5-12(16)9-11-10-15-14-7-3-2-6-13(11)14/h2-3,6-7,10,12,15H,4-5,8-9H2,1H3; Key:HCTCDEAMCNSARD-UHFFFAOYSA-N;

3-(N-methylpyrrolidin-3-ylmethyl)indole (MPMI) is a tryptamine derivative which acts as a serotonin receptor agonist. It has been studied as an analogue and trace impurity of the anti-migraine drug eletriptan but is otherwise little known.^[1]^[2]

References

^ FI 105812, Wythes MJ, Macor JE, "Menetelmä terapeuttisesti käyttökelpoisten indolijohdannaisten valmistamiseksi", issued 14 April 1993, assigned to Pfizer, Inc.
^ US 5607951, Macor JE, Wythes MJ, "Indole derivatives", issued 4 March 1997, assigned to Pfizer, Inc.

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[1] FI 105812, Wythes MJ, Macor JE, "Menetelmä terapeuttisesti käyttökelpoisten indolijohdannaisten valmistamiseksi", issued 14 April 1993, assigned to Pfizer, Inc.

[2] US 5607951, Macor JE, Wythes MJ, "Indole derivatives", issued 4 March 1997, assigned to Pfizer, Inc.

[1]

[2]

MPMI (drug)

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Identifiers

IUPAC name 3-[(1-methylpyrrolidin-2-yl)methyl]-1H-indole
CAS Number	143321-54-4^Y 143322-55-8 (R enantiomer)
PubChem CID	53870442
ChemSpider	68007055
Chemical and physical data
Formula	C₁₄H₁₈N₂
Molar mass	214.312 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CN1CCCC1CC2=CNC3=CC=CC=C32
InChI InChI=1S/C14H18N2/c1-16-8-4-5-12(16)9-11-10-15-14-7-3-2-6-13(11)14/h2-3,6-7,10,12,15H,4-5,8-9H2,1H3 Key:HCTCDEAMCNSARD-UHFFFAOYSA-N

MPMI (drug)

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References

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