N1-Methyl-lysergic acid diethylamide
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The topic of this article may not meet Wikipedia's general notability guideline. (April 2015) |
Clinical data | |
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Other names | MLD-41; N1-Methyl-Lysergic Acid Diethylamide |
Routes of administration | Oral |
Pharmacokinetic data | |
Metabolism | Hepatic |
Excretion | Renal |
Identifiers | |
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CAS Number | |
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CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C21H27N3O |
Molar mass | 337.467 g·mol−1 |
3D model (JSmol) | |
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N1-Methyl-lysergic acid diethylamide (MLD-41) is a derivative of LSD that has about one-third the psychoactive effects. It has been studied in cross-tolerance of LSD.[1]
Metabolism of other 1-methylated-ergoloids to their secondary amine derivatives has been frequently noted in mammals.[2]
References
- ^ Abramson HA, Rolo A, Sklarofsky B, Stache J (January 1960). "Production of cross-tolerance to psychosis-producing doses of lysergic acid diethylamide and psilocybin". The Journal of Psychology. 49 (1): 151–4. doi:10.1080/00223980.1960.9916396.
- ^ Müller-Schweinitzer E, Tapparelli C (March 1986). "Methylergometrine, an active metabolite of methysergide". Cephalalgia: An International Journal of Headache. 6 (1): 35–41. doi:10.1046/j.1468-2982.1986.0601035.x. PMID 3698092. S2CID 5778173.
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