Emibetuzumab

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Emibetuzumab
Monoclonal antibody
Type?
SourceHumanized (from mouse)
TargetHGFR
Clinical data
Other namesLY2875358
ATC code
  • none
Identifiers
CAS Number
  • 1365287-97-3
IUPHAR/BPS
ChemSpider
  • none
UNII
Chemical and physical data
FormulaC6356H9810N1694O2014S48
Molar mass143719.12 g·mol−1

Emibetuzumab (INN[1]) (LY2875358) is a humanized monoclonal antibody designed for the treatment of cancer.[2] It is in phase II trials for patients with NSCLC[3]

This drug was developed by Eli Lilly & Company.

References

  1. ^ World Health Organization (2014). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 111" (PDF). WHO Drug Information. 28 (2).
  2. ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Emibetuzumab, American Medical Association.
  3. ^ Camidge DR, Moran T, Demedts I, Grosch H, Di Mercurio JP, Mileham KF, et al. "A randomized, open-label, phase 2 study of emibetuzumab plus erlotinib (LY+E) and emibetuzumab monotherapy (LY) in patients with acquired resistance to erlotinib and MET diagnostic positive (MET Dx+) metastatic NSCLC".