Neurotrophin-4

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NTF4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNTF4, GLC10, GLC1O, NT-4, NT-4/5, NT-5, NT4, NT5, NTF5, neurotrophin 4
External IDsOMIM: 162662 MGI: 97381 HomoloGene: 4503 GeneCards: NTF4
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006179
NM_001395489

NM_198190

RefSeq (protein)

NP_006170

NP_937833

Location (UCSC)Chr 19: 49.06 – 49.07 MbChr 7: 45.06 – 45.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Neurotrophin-4 (NT-4)[5], also known as neurotrophin-5 (NT-5), is a protein that in humans is encoded by the NTF4 gene.[6] It is a neurotrophic factor that signals predominantly through the TrkB receptor tyrosine kinase[7][8].

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000225950 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000074121 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ibanez CF, Ernfors P, Timmusk T, IP NY, Arenas E, Yancopoulos GD, Persson H (Apr 1993). "Neurotrophin-4 is a target-derived neurotrophic factor for neurons of the trigeminal ganglion". Development. 117 (4): 1345–1353. doi:10.1242/dev.117.4.1345. PMID 8404536.
  6. ^ "Entrez Gene: neurotrophin 4".
  7. ^ Klein R, Lamballe F, Bryant S, Barbacid M (May 1992). "The trkB tyrosine protein kinase is a receptor for neurotrophin-4". Neuron. 8 (5): 947–956. doi:10.1016/0896-6273(92)90209-v. PMID 1375038.
  8. ^ Ip NY, Stitt TN, Tapley P, Klein R, Glass DJ, Fandl J, Greene LA, Barbacid M, Yancopoulos GD (Feb 1993). "Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells". Neuron. 10 (2): 137–149. doi:10.1016/0896-6273(93)90306-c. PMID 7679912.

Further reading

External links