Talastine
Jump to navigation
Jump to search
Clinical data | |
---|---|
ATC code | |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C19H21N3O |
Molar mass | 307.397 g·mol−1 |
3D model (JSmol) | |
| |
| |
(verify) |
Talastine (trade name Ahanon) is an antihistamine.[1]
Synthesis
The amide proton from 4-Benzylphalazone is abstracted with KOH, which is then alkylated with dimethylaminoethyl chloride.[2][3]
References
- ^ Richter G, Kühn E (1990). "[Talastine (Ahanon) as a cause of allergic drug exanthema]". Dermatologische Monatschrift (in German). 176 (2–3): 111–3. PMID 1973126.
- ^ DE 1046625, Engelbrecht, et al., issued 1958, assigned to VEB Deutsches Hydrierwerk Rodleben
- ^ US 3017411, Engelbrecht, et al., issued 1962, assigned to VEB Deutsches Hydrierwerk Rodleben
External links
- "Talastine". Comparative Toxicogenomics Database.
- Talastine at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Categories:
- CS1 German-language sources (de)
- Articles with short description
- Short description matches Wikidata
- Articles without EBI source
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Drugs with no legal status
- Phthalazines
- H1 receptor antagonists
- Lactams
- Benzyl compounds
- All stub articles
- Respiratory system drug stubs