Diffusely adherent E. coli
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| Diffusely adherent E. coli | |
|---|---|
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| Adherence mechanism of DAEC -a)DAEC attaches to the host epithelial cells by Afa/Dr adhesions b)adhesion molecules internalize the DAEC c) DAF cells provide a niche for DAEC replication[1] | |
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| Specialty | Infectious disease |
Diffusely adherent Escherichia coli (DAEC) is a diarrheagenic E. coli pathogroup. It harbors genes encoding for Afa/Dr adhesins, which can cause diarrhea illness in individuals.[2]
DAEC strains attach to brush borders of epithelial cells, it then rearranges the cytoskeletal structures of microvilli .In terms of internalization it is mediated via microtubules. After several further cell processes ,PMN crosses epithelium barrier which provokes the creation of TNF-α and IL-1β which in turn regulate DAF, hence energizing bacterial replication.[1][3]
See also
- Enterotoxigenic Escherichia coli
- Enteropathogenic E. coli
- Enteroinvasive Escherichia coli
- Enteroaggregative Escherichia coli
References
- ↑ 1.0 1.1 Govindarajan, Deenadayalan Karaiyagowder; Viswalingam, Nandhini; Meganathan, Yogesan; Kandaswamy, Kumaravel (September 2020). "Adherence patterns of Escherichia coli in the intestine and its role in pathogenesis". Medicine in Microecology. 5: 100025. doi:10.1016/j.medmic.2020.100025. Archived from the original on 2023-04-03. Retrieved 2024-03-24.
- ↑ Meza-Segura, Mario; Estrada-Garcia, Teresa (2016). "Diffusely Adherent Escherichia coli". Escherichia coli in the Americas. Springer International Publishing: 125–147. doi:10.1007/978-3-319-45092-6_6. Archived from the original on 16 June 2018. Retrieved 24 March 2024.
- ↑ Mansan-Almeida, Rosane; Pereira, Alex Leite; Giugliano, Loreny Gimenes (1 February 2013). "Diffusely adherent Escherichia colistrains isolated from children and adults constitute two different populations". BMC Microbiology. 13 (1): 22. doi:10.1186/1471-2180-13-22. ISSN 1471-2180. Archived from the original on 10 December 2023. Retrieved 24 March 2024.