Rickettsia akari

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Rickettsia akari
Scientific classification edit
Domain: Bacteria
Phylum: Pseudomonadota
Class: Alphaproteobacteria
Order: Rickettsiales
Family: Rickettsiaceae
Genus: Rickettsia
Species group: Spotted fever group
R. akari
Binomial name
Rickettsia akari
Huebner, 1946

Rickettsia akari is a species of Rickettsia which causes rickettsialpox.[1][2]

After a 1946 outbreak of a rickettsial-type disease at an apartment complex in Kew Gardens, Queens, an investigation was performed to identify the source of the infections. The incinerators in the buildings were not operated on a daily basis, leading to a buildup in food waste and attracting mice that were rampant throughout the building. The Mus musculus mice were found to be carrying mites, identified as the house mouse mite, Allodermanyssus sanguineus. Self-trained entomologist Charles Pomerantz asked permission to search the site and found the mites at various sites throughout the building, with blood-engorged mites found near chutes leading to the incinerator. The mites were collected and brought to a laboratory of the United States Public Health Service, which found in the mites an organism that had also been isolated from the mice, and from the blood of individuals infected with the disease.[3]

The organism was given its name by physician Robert Huebner, one of the scientists who had tracked down the source of the original 1946 epidemic; the akari portion of the bacteria's name represents the Greek word for "mite".[4]

While active efforts to exterminate mice from buildings has greatly reduced recurrences of the diseases, a July 2002 report from the Centers for Disease Control and Prevention report a recent case in North Carolina, noting that cases have been reported in Croatia and Ukraine and that the R. akari organism may exist in "sylvan cycles", such as its isolation from voles in Korea.[5]

Multiple papulovesicles involving the upper trunk on individual with rickettsialpox.

See also


  1. "rickettsialpox" at Dorland's Medical Dictionary
  2. Mayer, Gene. "Bacteriology: Ch. 21: Rickettsia, Orientia, Ehrlichia, Anaplasma, Coxiella and Bartonella". Microbiology and Immunology On-line. University of South Carolina School of Medicine. Archived from the original on 2014-01-18. Retrieved 2022-10-02.
  3. Greenberg M, Pellitteri OJ, Jellison WL (July 1947). "Rickettsialpox-A Newly Recognized Rickettsial Disease : III. Epidemiology" (PDF). Am J Public Health Nations Health. 37 (7): 860–8. doi:10.2105/ajph.37.7.860. PMC 1623794. PMID 18016565.
  4. Beeman, Edward A. (2005). "Robert J. Huebner, M.D.:A Virologist's Odyssey" (PDF). National Institutes of Health. Archived (PDF) from the original on 2015-02-13. Retrieved 2022-10-02.
  5. Krusell A, Comer JA, Sexton DJ (July 2002). "Rickettsialpox in North Carolina: a case report". Emerging Infect. Dis. 8 (7): 727–8. doi:10.3201/eid0807.010501. PMC 2730333. PMID 12095443.