Estradiol valerate/dienogest
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Combination drug
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Combination of | |
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Estradiol valerate | Estrogen |
Dienogest | Progestogen |
Clinical data | |
Trade names | Lafamme, Natazia, Qlaira |
Other names | EV/DNG; SH T00658ID; Bay 86-5027; BAY86-5027 |
AHFS/Drugs.com | Professional Drug Facts |
MedlinePlus | a601050 |
License data | |
Pregnancy category | |
Routes of administration | By mouth |
Drug class | Estrogen; Progestogen |
ATC code | |
Legal status | |
Legal status |
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Identifiers | |
CAS Number | |
PubChem CID | |
KEGG |
Estradiol valerate/dienogest (EV/DNG), sold under the brand names Lafamme, Natazia and Qlaira among others, is a combination product of estradiol valerate, an estrogen, and dienogest, a progestogen, which is used in menopausal hormone therapy in and as a birth control pill to prevent pregnancy in women. It is taken by mouth.
Birth control pills containing EV/DNG are associated with a significantly increased risk of venous thromboembolism.[2] However, they are associated with a significantly lower risk of venous thromboembolism than birth control pills containing ethinylestradiol and a progestin.[2]
See also
- Estradiol valerate/cyproterone acetate
- Estradiol/nomegestrol acetate
- List of combined sex-hormonal preparations
References
- ^ a b c "Dienogest / estradiol (Natazia) Use During Pregnancy". Drugs.com. 27 January 2020. Retrieved 18 March 2020.
- ^ a b Fruzzetti F, Cagnacci A (2018). "Venous thrombosis and hormonal contraception: what's new with estradiol-based hormonal contraceptives?". Open Access J Contracept. 9: 75–79. doi:10.2147/OAJC.S179673. PMC 6239102. PMID 30519125.
External links
- "Dienogest mixture with Estradiol valerate". Drug Information Portal. U.S. National Library of Medicine.
Progestogens (and progestins) |
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Antiprogestogens |
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ERTooltip Estrogen receptor |
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GPERTooltip G protein-coupled estrogen receptor |
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PRTooltip Progesterone receptor |
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mPRTooltip Membrane progesterone receptor (PAQRTooltip Progestin and adipoQ receptor) |
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