|Other names: Cartilage tumors|
|Osteochondroma, a common type of non-cancerous chondrogenic tumors|
|Types||Noncancerous (benign), cancerous (malignant) or intermediate locally aggressive|
|Diagnostic method||Medical imaging|
|Prognosis||Varies with type|
|Frequency||Commonest type of primary bone tumor|
Chondrogenic tumors, also known as cartilage tumors, are a type of bone tumor that develop in cartilage, and are classified into non-cancerous, cancerous and intermediate locally aggressive types.
Diagnosis is made using medical imaging, often when investigating another problem. Tests include X-ray, CT scan, Magnetic resonance imaging and Positron emission tomography. The precise diagnosis is based on histology.
|Bizarre parosteal osteochondromatous proliferation|
|Atypical cartilaginous tumor (ACT)/Chondrosarcoma grade I in limbs|
|Cancerous (Chondrosarcoma)||Conventional chondrosarcoma grade I (axial skeleton)-III|
|Clear cell chondrosarcoma|
Diagnosis includes medical imaging. Distinguishing a large non-cancerous cartilage tumor, such as an enchondroma, from a chondrosarcoma grade I or atypical cartilaginous tumour is difficult. Often, there are overlapping histological features.
Chondrogenic tumors are the most common type of bone tumor that arise from bone itself. Cancerous chondrogenic tumors represent around 25% of all cancerous bone tumors. Osteochondroma and enchondroma are the most common non-cancerous types, and conventional chondrosarcoma is the most common cancerous type.
Of all chondrogenic tumors, 28.5% are osteochondroma, 29.1% enchondroma, 21.7% conventional chondrosarcoma grade I-III, less than 5% are subungual exostosis and bizarre parosteal osteochondromatous proliferation combined, and the least common is mesenchymal chondrosarcoma at less than 1%, as reported by the WHO in 2020.
- Engel, Hannes; Herget, Georg W.; Füllgraf, Hannah; Sutter, Reto; Benndorf, Matthias; Bamberg, Fabian; Jungmann, Pia M. (March 2021). "Chondrogenic Bone Tumors: The Importance of Imaging Characteristics". RoFo: Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin. 193 (3): 262–275. doi:10.1055/a-1288-1209. ISSN 1438-9010. PMID 33152784. Archived from the original on 2021-07-09. Retrieved 2021-07-04.
- Soft Tissue and Bone Tumours: WHO Classification of Tumours. International Agency for Research on Cancer. 2020. p. 338. ISBN 978-92-832-4502-5. Archived from the original on 2021-06-13. Retrieved 2021-07-04.
- Bocklage, Therese J.; Quinn, Robert; Verschraegen, Claire; Schmit, Berndt (2014). "16. Cartilaginous tumours of bones and joints". Bone and Soft Tissue Tumors: A Multidisciplinary Review with Case Presentations. London: JP Medical Ltd. pp. 366–409. ISBN 978-1-907816-22-2. Archived from the original on 2021-07-09. Retrieved 2021-08-21.
- Choi, Joon Hyuk; Ro, Jae Y. (1 May 2021). "The 2020 WHO Classification of Tumors of Bone: An Updated Review". Advances in Anatomic Pathology. 28 (3): 119–138. doi:10.1097/PAP.0000000000000293. ISSN 1533-4031. PMID 33480599. Archived from the original on 23 May 2021. Retrieved 4 July 2021.
- Cleven, Arjen H. G.; Bovée, Judith V. M. G. (1 October 2020). "Clinicopathological features and differential diagnosis of chondrogenic tumours". Diagnostic Histopathology. 26 (10): 484–491. doi:10.1016/j.mpdhp.2020.07.006. ISSN 1756-2317. Archived from the original on 27 August 2021. Retrieved 6 July 2021.
- Ahlawat, Shivani; Fayad, Laura M. (10 August 2020). "Revisiting the WHO classification system of bone tumours: emphasis on advanced magnetic resonance imaging sequences. Part 2". Polish Journal of Radiology. 85: e409–e419. doi:10.5114/pjr.2020.98686. ISSN 1733-134X. PMID 32999694. Archived from the original on 28 August 2021. Retrieved 7 July 2021.
- Suster, David; Hung, Yin Pun; Nielsen, G. Petur (1 January 2020). "Differential Diagnosis of Cartilaginous Lesions of Bone". Archives of Pathology & Laboratory Medicine. 144 (1): 71–82. doi:10.5858/arpa.2019-0441-RA. ISSN 0003-9985. Archived from the original on 19 July 2021. Retrieved 17 July 2021.