|Other names: Carney bone tumor (not recommended)|
|Symptoms||Painless lump in a child <2-years|
|Risk factors||Carney complex|
|Differential diagnosis||chondromyxoid fibroma, myxoma, mesenchymal hamartoma, chondrosarcoma with myxoid change, fibrocartilaginous mesenchymoma.|
|Frequency||Rare, age <2 years|
Osteochondromyxoma is a type of non-cancerous bone tumor of the cartilaginous type, which typically presents with a painless lump in a child under the age of 2-years. Sometimes there are no symptoms and the tumor is found when investigating another problem or as part of the tests when suspecting the genetic condition Carney complex.
Diagnosis involves MRI. Differential diagnoses include chondromyxoid fibroma and myxoma.
Treatment requires surgical excision, but if not completely removed then recurrence is common.
Osteochondromyxomas are rare and account for around 1% of all people with Carney complex.
Signs and symptoms
It typically presents with a painless lump in a child under the age of 2-years. It may be detected on routine imaging in people with Carney complex. The lump may be associated with soft tissue swelling and pressure effects on nearby structures.
Diagnosis involves medical imaging, with MRI being more precise. It appears as a well-defined expansile mass of bone with varying degrees of lucency.
Similar clinical features and findings can occur with chondromyxoid fibroma, myxoma, mesenchymal hamartoma, chondrosarcoma with myxoid change, and fibrocartilaginous mesenchymoma.
Treatment and Outcomes
Surgical excision generally results in a cure. Recurrence is common if the whole tumor is not cut out completely. It does not spread.
Osteochondromyxomas are rare and account for around 1% of all people with Carney complex, a syndrome that predisposes to cancer. It can occur in adults.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 "Osteochondromyxoma". Soft Tissue and Bone Tumours: WHO Classification of Tumours. International Agency for Research on Cancer. 2020. pp. 365–367. ISBN 978-92-832-4502-5. Archived from the original on 2021-06-13. Retrieved 2021-07-06.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Golden, Todd; Siordia, Juan A. (12 July 2016). "Osteochondromyxoma: Review of a rare carney complex criterion". Journal of Bone Oncology. 5 (4): 194–197. doi:10.1016/j.jbo.2016.07.002. ISSN 2212-1366. PMID 28008382. Archived from the original on 28 August 2021. Retrieved 6 July 2021.
- ↑ 3.0 3.1 3.2 Ahlawat, Shivani; Fayad, Laura M. (10 August 2020). "Revisiting the WHO classification system of bone tumours: emphasis on advanced magnetic resonance imaging sequences. Part 2". Polish Journal of Radiology. 85: e409–e419. doi:10.5114/pjr.2020.98686. ISSN 1733-134X. PMID 32999694. Archived from the original on 28 August 2021. Retrieved 7 July 2021.
- ↑ Bocklage, Therese J.; Quinn, Robert; Verschraegen, Claire; Schmit, Berndt (2014). "16. Cartilaginous tumours of bones and joints". Bone and Soft Tissue Tumors: A Multidisciplinary Review with Case Presentations. London: JP Medical Ltd. p. 379. ISBN 978-1-907816-22-2. Archived from the original on 2021-07-09. Retrieved 2021-07-06.