Atypical cartilaginous tumor

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Atypical cartilaginous tumor

Atypical cartilaginous tumor, also known as chondrosarcoma grade I, is a low-grade locally aggressive bone tumor of the cartilaginous type, with intermediate potential to become cancerous, arising from long and short tubular bones.[1][2][3]


Both atypical cartilaginous tumor and chondrosarcoma grade I are low grade cartilaginous tumours that appear identical when looking under the microscope.[4] When found in the central skeleton including the pelvis, scapula, and base of skull, it is termed chondrosarcoma grade 1, and when found in an arm or leg it is termed atypical cartilaginous tumor.[4]


The term atypical cartilaginous tumor arose as a new concept in the fourth edition of the WHO classification of bone tumours (2013).[4]


  1. Dierselhuis, Edwin F. (2019). Advances of treatment in atypical cartilaginous tumours (PDF). The Netherlands: Gildeprint. p. 11. ISBN 978-90-9031884-4. Archived (PDF) from the original on 2021-08-27. Retrieved 2021-07-06.
  2. "Central atypical cartilaginous tumour / chondrosarcoma, grade 1". Soft Tissue and Bone Tumours: WHO Classification of Tumours. International Agency for Research on Cancer. 2020. p. 370-372. ISBN 978-92-832-4502-5. Archived from the original on 2021-06-13. Retrieved 2021-07-06.
  3. Cleven, Arjen H. G.; Bovée, Judith V. M. G. (1 October 2020). "Clinicopathological features and differential diagnosis of chondrogenic tumours". Diagnostic Histopathology. 26 (10): 484–491. doi:10.1016/j.mpdhp.2020.07.006. ISSN 1756-2317. Archived from the original on 27 August 2021. Retrieved 6 July 2021.
  4. 4.0 4.1 4.2 Suster, David; Hung, Yin Pun; Nielsen, G. Petur (1 January 2020). "Differential Diagnosis of Cartilaginous Lesions of Bone". Archives of Pathology & Laboratory Medicine. 144 (1): 71–82. doi:10.5858/arpa.2019-0441-RA. ISSN 0003-9985. Archived from the original on 19 July 2021. Retrieved 17 July 2021.