Granuloma faciale

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Granuloma faciale
Other names: GF

Granuloma faciale is an uncommon benign chronic skin disease of unknown origin characterized by single or multiple cutaneous nodules, usually occurring over the face.[1]: 836  Occasionally, extrafacial involvement is noted, most often on sun-exposed areas.


Skin biopsy for histopathology: Focal LCV, diffuse dermal neutrophilia with leukocytoclasia, tissue eosinophilia & perivascular fibrosis.

Differential diagnosis

The disease mimics many other dermatoses and can be confused with conditions, such as sarcoidosis, discoid lupus erythematosus, mycosis fungoides, and fixed drug eruption.[citation needed]


Topical corticosteriod, Intralesional corticosteroid, Dapsone, Colchicine, Antimalarial, Pulse dye laser, Carbon dioxide laser.


GF was first described in 1945 by John Edwin Mackonochie Wigley (1892–1962).[2]

Additional images

See also


  1. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.
  2. Wigley, J. E. (1945). "Eosinophilic Granuloma. ? Sarcoid of Boeck". Proceedings of the Royal Society of Medicine. 38 (3): 125–126. PMC 2181658. PMID 19992999.

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