Dermatosis papulosa nigra

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Dermatosis papulosa nigra
Dermatosis papulosa nigra (DermNet NZ lesions-dpn1).jpg
Dermatosis papulosa nigra

Dermatosis papulosa nigra (DPN) is a benign skin condition that presents as multiple small skin-colored or dark spots and bumps on dark-skinned individuals.[1]

DPN is extremely common, affecting up to 35% of Black people in general.[1]


The condition may be cosmetically undesirable to some.They should not be confused for Leser-Trélat sign, a sudden explosion of lesions due to a growing tumor. From a histological perspective, DPN resembles seborrheic keratoses.


The pathophysiology of DPN is unknown. Evidence of family history may suggest a genetic propensity.


DPN lesions are benign and no treatment generally is indicated unless lesions are cosmetically undesirable. Surgical options including curettage, cryotherapy and laser therapy are options.[2] Scarring, postoperative skin discoloration or keloid formation are potential complications. Therefore, conservative DPN treatment is advisable.


DPN is not a pre-malignant condition nor is it associated with any underlying systemic disease.[1] DPN lesions show no tendency to regress spontaneously, and often increase in size and number as an individual ages.


DPN affects up to 35% of the African American population in the USA.[3] Insufficient data is available on the international frequency of DPN. Lesions generally emerge during puberty, increasing steadily in number and size as an individual ages.[4] The incidence of DPN lesions increases with age.[1] Black people with a fair complexion have the lowest frequency of involvement. DPN also occurs among Asians and Polynesians, although the exact incidence is unknown. Females are affected more frequently than males. Dermatosis papulosa nigra generally emerges in adolescence and is rarely in persons younger than 7 years.[4]

See also


  1. 1.0 1.1 1.2 1.3 James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "29. Epidermal nevi, neoplasms, and cysts". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. p. 640. ISBN 978-0-323-54753-6. Archived from the original on 2023-12-01. Retrieved 2023-11-29.
  2. Kauh YC, McDonald JW, Rapaport JA, Ruschak PJ, Luscombe HA. A surgical approach for dermatosis papulosa nigra Archived 2017-11-01 at the Wayback Machine. Int J Dermatol. Dec 1983;22(10):590-2.
  3. Dunwell P, Rose A. Study of the skin disease spectrum occurring in an Afro-Caribbean population. Int J Dermatol. Apr 2003;42(4):287-9.
  4. 4.0 4.1 Babapour R, Leach J, Levy H. Dermatosis papulosa nigra in a young child. Pediatr Dermatol. Dec 1993;10(4):356-8.

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