Tumid lupus erythematosus

From WikiProjectMed
Jump to navigation Jump to search
Tumid lupus erythematosus
Other names: "Lupus erythematosus tumidus"[1]
PMC3969703 IJD-59-210d-g001 (1).png
Tumid LE illustrating single erythematous, indurated, 3 cm-sized plaque

Tumid lupus erythematosus is a rare, but distinctive entity in which patients present with edematous erythematous plaques, usually on the trunk.[2]

Lupus erythematosus tumidus (LET) was reported by Henri Gougerot and Burnier R. in 1930. It is a photosensitive skin disorder, a different subtype of cutaneous lupus erythematosus (CLE) from discoid lupus erythematosus (DLE) or subacute CLE (SCLE).[3] LET is usually found on sun-exposed areas of the body. Skin lesions are edematous, urticarialike annular papules and plaques. Topical corticosteroids are not effective as treatment for LET, but many will respond to chloroquine. LET resolves with normal skin, no residual scarring, no hyperpigmentation or hypopigmentation. Cigarette smokers who have LET may not respond very well to chloroquine.[4][5]

It has been suggested that it is equivalent to Jessner lymphocytic infiltrate of the skin.[6]

See also


  1. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. Page 159. ISBN 0-7216-2921-0.
  3. Gougerot H, Burnier R. Lupus érythémateux "tumidus". Bull Soc Fr Dermatol Syphiligr. 1930;37:1291-1292.
  4. Kuhn A, Richter-Hintz D, Oslislo C, Ruzicka T, Megahed M, Lehmann P. Lupus erythematosus tumidus, a neglected subset of cutaneous lupus erythematosus. Report of 40 cases. Arch Dermatol. 2000;136(8):1033-1041.
  5. Callen JP. Management of skin disease in patients with lupus erythematosus. Best Pract Res Clin Rheumatol. 2002;16(2):245-264.
  6. "Jessner Lymphocytic Infiltration of the Skin: eMedicine Dermatology". Archived from the original on 2010-03-17. Retrieved 2010-05-22.