Elastosis perforans serpiginosa

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Elastosis perforans serpiginosa
Other names: EPS[1]
Elastosis perforans serpiginosa: Hyperkeratotic plaque of papules[2]

Elastosis perforans serpiginosa is a unique perforating disorder characterized by transepidermal elimination of elastic fibers and distinctive clinical lesions, which are serpiginous in distribution and can be associated with specific diseases.[3][4]


This dermatological condition is inherited in an autosomal dominant manner.[citation needed]


Histopathology of this condition

Histopathology of elastosis perforans serpiginosa: Degenerated elastic fibers and transepidermal perforating canals (arrow points at one of them)[2]

Additional images

See also


  1. "OMIM Entry - 130100 - ELASTOSIS PERFORANS SERPIGINOSA; EPS". omim.org. Archived from the original on 28 August 2021. Retrieved 19 April 2019.
  2. 2.0 2.1 Hosen, Mohammad J.; Lamoen, Anouck; De Paepe, Anne; Vanakker, Olivier M. (2012). "Histopathology of Pseudoxanthoma Elasticum and Related Disorders: Histological Hallmarks and Diagnostic Clues". Scientifica. 2012: 1–15. doi:10.6064/2012/598262. ISSN 2090-908X.
    -Creative Commons Attribution 3.0 Unported Archived 2011-02-23 at the Wayback Machine license
  3. Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). Page 1041. McGraw-Hill. ISBN 0-07-138076-0.
  4. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.

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External resources