PUVA keratosis

From WikiProjectMed
Jump to navigation Jump to search
PUVA keratosis
SymptomsSmall scaly bumps with a wide base and warty look[1]
Risk factorsPsoralen and ultraviolet A light therapy[1]
Diagnostic methodBy its appearance, skin biopsy[2]
Differential diagnosisActinic keratosis[1]
Frequency15%-30% after 5 to 8 years of PUVA exposure[1]

PUVA keratosis is a pre-cancerous keratotic skin lesion that arises from exposure to psoralen and ultraviolet A light therapy.[1] It presents as a small scaly bump in the skin with a wide base and warty look.[1]

It may appear similar to actinic keratosis, but differentiated by its appearance under the microscope; PUVA keratosis does not have solar elastosis.[2]

See also


  1. 1.0 1.1 1.2 1.3 1.4 1.5 DE, Elder; D, Massi; RA, Scolyer; R, Willemze (2018). "Premalignant keratoses: PUVA keratosis". WHO Classification of Skin Tumours. Vol. 11 (4th ed.). Lyon (France): World Health Organization. p. 53. ISBN 978-92-832-2440-2. Archived from the original on 2022-07-11. Retrieved 2022-08-13.
  2. 2.0 2.1 Johnstone, Ronald B. (2017). "31. Tumors of the epidermis". Weedon's Skin Pathology Essentials (2nd ed.). Elsevier. p. 514. ISBN 978-0-7020-6830-0. Archived from the original on 2021-05-25. Retrieved 2022-08-13.