Fluperolone acetate

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Fluperolone acetate
Fluperolone acetate.svg
Clinical data
Other names9α-Fluoro-11β,17α,21-trihydroxy-21-methylpregna-1,4-diene-3,20-dione 21-acetate
ATC code
Identifiers
  • (2S)-1-[(1R,2S,10S,11S,14R,15S,17S)-1-fluoro-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-14-yl]-1-oxopropan-2-yl acetate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.016.662 Edit this at Wikidata
Chemical and physical data
FormulaC24H31FO6
Molar mass434.504 g·mol−1
3D model (JSmol)
  • C[C@@H](C(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)O)OC(=O)C
  • InChI=1S/C24H31FO6/c1-13(31-14(2)26)20(29)23(30)10-8-17-18-6-5-15-11-16(27)7-9-21(15,3)24(18,25)19(28)12-22(17,23)4/h7,9,11,13,17-19,28,30H,5-6,8,10,12H2,1-4H3/t13-,17-,18-,19-,21-,22-,23-,24-/m0/s1
  • Key:HHPZZKDXAFJLOH-QZIXMDIESA-N
  (verify)

Fluperolone acetate is a corticosteroid. It has been used topically.[1]

References

  1. ^ Thorne N (March 1963). "A clinical trial of Fluperolone, a new topical steroid". Postgraduate Medical Journal. 39 (449): 159–60. doi:10.1136/pgmj.39.449.159. PMC 2482046. PMID 13984971.