Mestranol/hydroxyprogesterone acetate
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Combination drug
Combination of | |
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Mestranol | Estrogen |
Hydroxyprogesterone acetate | Progestogen |
Clinical data | |
Trade names | Hormolidin |
Other names | ME/OHPA; EEME/OHPA |
Routes of administration | By mouth |
Drug class | Estrogen; Progestogen |
Mestranol/hydroxyprogesterone acetate (ME/OHPA), sold under the brand name Hormolidin, is a combination medication of mestranol (ME), an estrogen, and hydroxyprogesterone acetate (OHPA), a progestin, which was reportedly used as a sequential combined birth control pill for women in the early 1970s.[1] It was formulated as oral tablets and contained 16 tablets of 80 μg ME, 5 tablets of 80 μg ME and 100 mg OHPA, and 7 placebo tablets (28 tablets in total).[1] The medication was manufactured by the pharmaceutical company Gador in Argentina.[1]
See also
References
- ^ a b c Rudel HW, Kinel FA (September 1972). "Oral Contraceptives. Human Fertility Studies and Side Effects". In Tausk M (ed.). Pharmacology of the Endocrine System and Related Drugs: Progesterone, Progestational Drugs and Antifertility Agents. Vol. II. Pergamon Press. pp. 385–469. ISBN 978-0080168128. OCLC 278011135.
Progestogens (and progestins) |
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Antiprogestogens |
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ERTooltip Estrogen receptor |
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GPERTooltip G protein-coupled estrogen receptor |
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PRTooltip Progesterone receptor |
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mPRTooltip Membrane progesterone receptor (PAQRTooltip Progestin and adipoQ receptor) |
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