|Trade names||Naftin, Exoderil, others|
|Main uses||Athlete's foot, joke itch, ring worm|
|Side effects||Irritation, redness, itching, burning, allergic reaction|
|Chemical and physical data|
|Molar mass||287.406 g·mol−1|
|(what is this?)|
Naftifine sold under the brand name Naftin among others, is an antifungal medication used to treat athlete's foot, joke itch, and ring worm. While it has some benefit against candidiasis other medications are better. It is applied to the skin as a cream or gel.
Side effects occur in less than 5% of people. These may include irritation, redness, itching, burning, and allergic reaction. There is no evidence of harm in pregnancy, though such use is not well studied. It is similar to terbinafine and is believed to work by blocking sterol biosynthesis.
Mechanism of action
- Gupta, Aditya K.; Mays, Rachel R.; Folley, Kelly A. (2019). "42. Topical antifungal agents". In Wolverton, Stephen E.; Wu, Jashin J. (eds.). Comprehensive Dermatologic Drug Therapy (4th ed.). Elsevier. p. 486. ISBN 978-0-323-61211-1.
- "Naftifine Monograph for Professionals". Drugs.com. Retrieved 11 November 2021.
- "Naftifine topical Use During Pregnancy". Drugs.com. Retrieved 11 November 2021.
- Ritter, James M.; Flower, Rod; Henderson, Graeme; Loke, Yoon Kong; Rang, Humphrey P. (2020). "54. Antifungal drugs". Rang & Dale's Pharmacology. Elsevier. pp. 690–695. ISBN 978-0-7020-7448-6.
- "Naftifine Prices, Coupons & Savings Tips". GoodRx. Retrieved 11 November 2021.
- Robertson Dirk B, Maibach Howard I, "Chapter 61. Dermatologic Pharmacology" (Chapter). Bertram G. Katzung, Susan B. Masters, Anthony J. Trevor: Basic & Clinical Pharmacology, 11e: http://www.accesspharmacy.com/content.aspx?aID=4517257 Archived 2012-03-03 at the Wayback Machine.
- Micromedex DRUGDEX Drug Point: Naftifine Hydrochloride. Accessed at www.thomsonhc.com/../BeginWith#secN10184 Archived 2019-12-17 at the Wayback Machine, February 18, 2010.
- AccessPharmacy: Drug Monographs: Naftifine. Accessed at http://www.accesspharmacy.com/drugContentPopup.aspx?mid=6620§ion=10 Archived 2012-03-03 at the Wayback Machine, February 18, 2010.