DPT-Hib vaccine

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DPT-Hib vaccine
Combination of
Diphtheria vaccineVaccine
Tetanus vaccineVaccine
Pertussis vaccineVaccine
Hib vaccineVaccine
Trade namesTetramune
Clinical data
  • US: C (Risk not ruled out)
Routes of
Intramuscular injection
External links
AHFS/Drugs.comMicromedex Detailed Consumer Information
ATC code

DPT-Hib vaccine is a combination vaccine that protects against 4 diseases; diphtheria, tetanus, whooping cough, and Haemophilus influenzae disease.[1]

A branded formulation was marketed in the US as Tetramune by Lederle Praxis Biologicals (subsequently acquired by Wyeth).[2] Tetramune has since been discontinued.[3][4]


  1. "Diphtheria and Tetanus Toxoids and Pertussis Vaccine Adsorbed and Haemophilus B Conjugate Vaccine (Systemic)". Drugs.com. Archived from the original on 15 July 2018. Retrieved 15 July 2018.
  2. Centers for Disease Control Prevention (CDC) (April 1993). "FDA approval of use of a new Haemophilus b conjugate vaccine and a combined diphtheria-tetanus-pertussis and Haemophilus b conjugate vaccine for infants and children". MMWR. Morbidity and Mortality Weekly Report. Centers for Disease Control and Prevention. 42 (15): 296–8. PMID 8479415. Archived from the original on 25 June 2017. Retrieved 15 July 2018.
  3. "Selected Discontinued U.S. Vaccines" (PDF). Centers for Disease Control and Prevention. Archived (PDF) from the original on 23 November 2017. Retrieved 15 July 2018.
  4. Zarei AE, Almehdar HA, Redwan EM (2016). "Hib Vaccines: Past, Present, and Future Perspectives". Journal of Immunology Research. 2016: 7203587. doi:10.1155/2016/7203587. PMC 4745871. PMID 26904695. Table 1