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Other names: Bacterial pseudomycosis
SpecialtyInfectious disease

Botryomycosis is a rare chronic granulomatous bacterial infection that affects the skin, and sometimes the viscera.[1]

Botryomycosis has been known to affect humans, horses, cattle, swine, dogs and cats.

Signs and symptoms

Associated conditions

There are only a handful of documented cases of botryomycosis in humans, and its pathogenesis is not completely understood. However, it is usually described in individuals with impaired immunity, or with an underlying disease such as diabetes mellitus, cystic fibrosis or HIV infection.


Staphylococcus aureus is usually the organism that causes the infection,[2] however it can also be caused by Pseudomonas aeruginosa or several other species of bacteria. The anatomic structure of its lesion is similar to that of actinomycosis and eumycetoma, and its granules resemble the sulfur granules of actinomycosis.



The disease was originally discovered by Otto Bollinger (1843–1909) in 1870, and its name was coined by Sebastiano Rivolta (1832–1893) in 1884. The name refers to its grape-like granules (Gr. botryo = grapes) and the mistakenly implied fungal etiology (Gr. mykes = fungus).[3] In 1919 the bacterial origin of the infection was discovered.


  1. James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "14. Bacterial infections". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. p. 256-257. ISBN 978-0-323-54753-6. Archived from the original on 2022-06-06. Retrieved 2022-05-29.
  2. "botryomycosis" at Dorland's Medical Dictionary
  3. Medscape Today Archived 2015-02-01 at the Wayback Machine Primary Pulmonary Botryomycosis

Concise Review of Veterinary Microbiology - Quinn and Markey 2003

External links