List of skin tumors

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Skin tumors

Skin tumors are generally divided according to the skin cell they arise from.[1][2][3]

Keratinocytic/epidermal tumors

Type Sub-type Other types Signs/symptoms Image
Carcinomas Basal-cell carcinoma[1] Nodule

Painless small raised bump in the skin, which may be shiny with overlying small blood vessels, and have a central dip or ulcer, crusting, or blood.[4]

Squamous cell skin cancer[1] Ulcer
Squamous cell carcinoma in situ[1] Nodule
Merkel cell carcinoma[1] Nodule
Carcinomas precursors and noncancerous simulants Premalignant keratoses Actinic keratosis
Arsenical keratosis
PUVA keratosis
Verrucas Verruca vulgaris
Verruca plantaris
Verruca plana
Benign acanthomas/keratoses[1] Seborrheic keratosis
Solar lentigo
Lichen planus-like keratosis
Clear cell acanthoma
Large cell acanthoma
Warty dyskeratoma
Other benign keratoses

Melanocytic tumors

Type Types Signs/symptoms Image
Melanocytic tumors in intermittently sun-exposed skin[3] Superficial spreading melanoma
Simple lentigo and lentiginous melanocytic nevus
Junctional, compound, and dermal nevi
Dysplastic nevus
Nevus spilus
Special-site nevi (of the breast, axilla, scalp, and ear)
Halo nevus
Meyerson nevus
Recurrent nevus Macule[3]
Deep penetrating naevus and melanocytoma Papule[3][5]
Pigmented epithelioid melanocytoma
Combined nevus, including combined BAP1-inactivated naevus/ melanocytoma
Melanocytic tumors in chronically sun-exposed skin Lentigo maligna melanoma
Desmoplastic melanoma
Spitz tumors Malignant Spitz tumour (Spitz melanoma)
Spitz nevus
Pigmented spindle cell nevus (Reed nevus)
Melanocytic tumors in acral skin Acral melanoma
Acral nevus
Genital and mucosal melanocytes tumors Mucosal melanomas (genital, oral, sinonasal)
Genital naevus
Melanocytic tumors arising in blue nevus Melanoma arising in blue naevus
Blue naevus and cellular blue naevus
Mongolian spot
Naevus of Ito
Naevus of Ota
Melanocytic tumors arising in congenital nevus Melanoma arising in giant congenital naevus
Congenital melanocytic naevus
Proliferative nodules in congenital melanocytic naevus
Ocular melanocytic tumors Uveal melanoma
Conjunctival melanoma
Conjunctival melanocytic intraepithelial neoplasia/primary acquired melanosis
Conjunctival nevus
Nodular, nevoid, and metastatic melanoma Nodular melanoma
Nevoid melanoma
Metastatic melanoma

Skin tumors of blood and lymphoid origin

Type Notes Image
Mycosis fungoides [6]
Sézary disease [6]
Cutaneous adult T-cell lymphoma
Lymphomatoid granulomatosis
Langerhans cell histiocytosis
Rosai-Dorfman disease
Erdheim-Chester disease
Cutaneous Mastocytosis

Soft tissue tumors

Haemangiomas

caption
Type Notes Image
Cherry angioma
Hobnail hemangioma
Sinusoidal hemangioma

Neural tumors

caption
Type Notes Image
Neurofibroma
Dermal nerve sheath myxoma

Appendageal tumors

Malignant tumors with apocrine and eccrine differentiation

Malignant tumors with apocrine and eccrine differentiation
Type Notes Image
Porocarcinoma
Hidradinocarcinoma
Mucinous carcinoma
Apocrine carcinoma
Cribriform carcinoma

Benign tumors with apocrine and eccrine differentiation

Benign tumors with apocrine and eccrine differentiation
Type Notes Image
Hidrocystoma
Syringoma
Poroma
Syringofibroadenoma

Malignant tumors with follicular differentiation

Malignant tumors with follicular differentiation
Type Notes Image
Pilomatrical carcinoma
Proliferating trichilemmal tumour
Trichoblastic carcinoma
Trichilemmal carcinoma

Benign tumors with follicular differentiation

Benign tumors with follicular differentiation
Type Notes Image
Trichoblastoma
Pilomatricoma
Trichilemmoma
Trichofolliculoma
Pilar sheath acanthoma
Tumor of the follicular infundibulum
Melanocytic matricoma
Spindle cell-predominant tricodiscoma

Tumors with sebaceous differentiation

Tumors with sebaceous differentiation
Type Notes Image
Sebaceous adenoma Single well-defined small yellowish bump in sun-damaged skin of usually the neck and face, of a person older than age 40 years.[7]
Sebaceous carcinoma
Sebaceoma

Site specific tumors

Site specific tumors
Type Notes Image
Mammary Paget disease
Extramammary Paget disease
Hidradinoma papilliferum

See also

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 DE, Elder; D, Massi; RA, Scolyer; R, Willemze (2018). "1. Keratinocytic/epidermal tumours". WHO Classification of Skin Tumours. Vol. 11 (4th ed.). Lyon (France): World Health Organization. pp. 23–64. ISBN 978-92-832-2440-2. Archived from the original on 2022-07-11. Retrieved 2022-08-08.
  2. Paller, Amy S.; Mancini, Anthony J. (2020). "9. Cutaneous tumors and tumor syndromes". Clinical Pediatric Dermatology: A Textbook of Skin Disorders of Childhood and Adolescence (6th ed.). St Louis, Missouri: Elsevier. pp. 227–267. ISBN 978-0-323-54988-2. Archived from the original on 2023-07-01. Retrieved 2023-06-12.
  3. 3.0 3.1 3.2 3.3 DE, Elder; D, Massi; RA, Scolyer; R, Willemze (2018). "2. Melanocytic tumours". WHO Classification of Skin Tumours. Vol. 11 (4th ed.). Lyon (France): World Health Organization. pp. 65–152. ISBN 978-92-832-2440-2. Archived from the original on 2022-07-11. Retrieved 2022-08-08.
  4. James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "29. Epidermal nevi, neoplasms, and cysts". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. pp. 648–651. ISBN 978-0-323-54753-6. Archived from the original on 2023-06-30. Retrieved 2023-06-12.
  5. Gill, P; Aung, PP (17 March 2022). "Conventional and Atypical Deep Penetrating Nevus, Deep Penetrating Nevus-like Melanoma, and Related Variants". Biology. 11 (3). doi:10.3390/biology11030460. PMID 35336833. Archived from the original on 6 July 2023. Retrieved 4 July 2023.
  6. 6.0 6.1 DE, Elder; D, Massi; RA, Scolyer; R, Willemze (2018). "4. Tumors of haemopoietic and lymphoid origin". WHO Classification of Skin Tumours. Vol. 11 (4th ed.). Lyon (France): World Health Organization. pp. 223–290. ISBN 978-92-832-2440-2. Archived from the original on 2022-07-11. Retrieved 2022-08-08.
  7. DE, Elder; D, Massi; RA, Scolyer; R, Willemze (2018). "3. Appendageal tumours: Sebaceous adenoma". WHO Classification of Skin Tumours. Vol. 11 (4th ed.). Lyon (France): World Health Organization. p. 213. ISBN 978-92-832-2440-2. Archived from the original on 2022-07-11. Retrieved 2022-08-08.