Desmoplastic melanoma

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Desmoplastic melanoma
Other names: Neurotropic melanoma,[1] or Spindled melanoma[1]
Desmoplastic melanoma

Desmoplastic melanoma is a rare cutaneous condition characterized by a deeply infiltrating type of melanoma[2]: 696  with an abundance of fibrous matrix.[3] It usually occurs in the head and neck region of older people with sun-damaged skin.[3] Diagnosis can be difficult as it has a similar appearance to sclerosing melanocytic nevi as well as some nonmelanocytic skin lesions such as scars, fibromas, or cysts.[3]

Desmoplastic melanomas tend to recur locally, with distant metastasis being less common.[3]

Between 1% and 4% of all melanomas in predominantly pale-skinned populations are desmoplastic melanomas.[4] The male to female ratio is 1.75:1.[4] The average age of onset is over 665 years.[4]

Signs and symptoms

See also


  1. 1.0 1.1 Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.
  3. 3.0 3.1 3.2 3.3 Busam, Klaus J. (2011). "Desmoplastic Melanoma". Clinics in Laboratory Medicine. 31 (2): 321–30. doi:10.1016/j.cll.2011.03.009. PMID 21549245.
  4. 4.0 4.1 4.2 DE, Elder; D, Massi; RA, Scolyer; R, Willemze (2018). "2. Melanocytic tumours: Desmoplastic melanoma". WHO Classification of Skin Tumours. Vol. 11 (4th ed.). Lyon (France): World Health Organization. pp. 105–107. ISBN 978-92-832-2440-2. Archived from the original on 2022-07-11. Retrieved 2022-08-12.

External links