Tretinoin/benzoyl peroxide
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Combination of | |
---|---|
Tretinoin | Retinoid |
Benzoyl peroxide | Oxidizing agent |
Clinical data | |
Trade names | Twyneo |
Other names | S6G5T-3 |
License data | |
Routes of administration | Topical |
ATC code | |
Legal status | |
Legal status | |
Identifiers | |
KEGG |
Tretinoin/benzoyl peroxide, sold under the brand name Twyneo, is a fixed-dose combination medication used for the treatment of acne.[1][2] It contains tretinoin, a vitamin A derivative, and benzoyl peroxide, an oxidizing agent.[3]
The combination was approved for medical use in the United States in July 2021.[2][4][5]
References
- ^ a b "Twyneo (tretinoin and benzoyl peroxide) cream, for topical use" (PDF). U.S. Food and Drug Administration.
- ^ a b "Sol-Gel Technologies Announces FDA Approval of Twyneo" (Press release). Sol-Gel Technologies Ltd. 27 July 2021. Retrieved 27 July 2021 – via GlobeNewswire.
- ^ Ochsendorf F (June 2015). "Clindamycin phosphate 1.2% / tretinoin 0.025%: a novel fixed-dose combination treatment for acne vulgaris". Journal of the European Academy of Dermatology and Venereology. 29 (Suppl 5): 8–13. doi:10.1111/jdv.13185. PMID 26059820. S2CID 29681121.
- ^ "Twyneo: FDA-Approved Drugs". U.S. Food and Drug Administration (FDA). Retrieved 27 July 2021.
- ^ "NDA Approval: Twyneo" (PDF). U.S. Food and Drug Administration. 26 July 2021.
External links
- "Tretinoin". Drug Information Portal. U.S. National Library of Medicine.
- "Benzoyl peroxide". Drug Information Portal. U.S. National Library of Medicine.
- Clinical trial number NCT03761784 for "A Study of S6G5T-3 in the Treatment of Acne Vulgaris" at ClinicalTrials.gov
- Clinical trial number NCT03761810 for "A Study of S6G5T 3 in the Treatment of Acne Vulgaris" at ClinicalTrials.gov
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