Polyostotic fibrous dysplasia

From WikiProjectMed
Jump to navigation Jump to search
Polyostotic fibrous dysplasia
Other names: Albright's disease[1]: 578 
PMC1562402 1746-160X-2-24-2.png
Leontiasis ossea and cervical cord contusion as rare complications of Polyostotic fibrous dysplasia- a,b)Hypertrophy of posterior elements c)diffuse cortical thickening on lateral skull d) diffuse thickening of lumbar vertebrae.

Polyostotic fibrous dysplasia is a form of fibrous dysplasia affecting more than one bone.[2] Fibrous dysplasia is a disorder where bone is replaced by fibrous tissue, leading to weak bones, uneven growth, and deformity. [3]

McCune-Albright syndrome includes polyostotic fibrous dysplasia as part of its presentation.[4] When polyostotic fibrous dysplasia manifests in the long bones, limping results; when it manifests in the face, asymmetric growth of the face can result.[3]

One treatment that has been used is bisphosphonates.[5]

See also


  1. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  2. "Fibrous Dysplasia: Overview - eMedicine Radiology". Archived from the original on 2012-07-05. Retrieved 2009-02-23.
  3. 3.0 3.1 Reference, Genetics Home. "McCune-Albright syndrome". Genetics Home Reference. Archived from the original on 2018-01-07. Retrieved 2018-10-30.
  4. Lee, Peter A. (5 December 1986). "McCune-Albright Syndrome: Long-term Follow-up". JAMA: The Journal of the American Medical Association. 256 (21): 2980–4. doi:10.1001/jama.1986.03380210076028. PMID 3773215.
  5. Khadilkar VV, Khadilkar AV, Maskati GB (September 2003). "Oral bisphosphonates in polyostotic fibrous dysplasia". Indian Pediatr. 40 (9): 894–6. PMID 14530553. Archived from the original on 2018-03-23. Retrieved 2021-06-26.

External links

External resources