IFNB1

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IFNB1
Protein IFNB1 PDB 1au1.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesIFNB1, IFB, IFF, IFNB, IFN-beta, interferon beta 1
External IDsOMIM: 147640 MGI: 107657 HomoloGene: 1640 GeneCards: IFNB1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002176

NM_010510

RefSeq (protein)

NP_002167

NP_034640

Location (UCSC)Chr 9: 21.08 – 21.08 MbChr 4: 88.44 – 88.44 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interferon beta is a protein that in humans is encoded by the IFNB1 gene.[5] The natural and recombinant protein forms have antiviral, antibacterial, and anticancer properties.

Interferon beta 1a (tradenames: Avonex and Rebif) and Interferon beta 1b (tradenames: Betaseron/Betaferon) are used as drugs.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171855 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048806 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: IFNB1 interferon, beta 1, fibroblast".

Further reading