TGF beta 2

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TGFB2
Protein TGFB2 PDB 1tfg.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTGFB2, LDS4, TGF-beta2, transforming growth factor beta 2, G-TSF
External IDsOMIM: 190220 MGI: 98726 HomoloGene: 2432 GeneCards: TGFB2
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003238
NM_001135599

NM_009367
NM_001329107

RefSeq (protein)

NP_001129071
NP_003229

NP_001316036
NP_033393

Location (UCSC)Chr 1: 218.35 – 218.44 MbChr 1: 186.35 – 186.44 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development (alternative names: Glioblastoma-derived T-cell suppressor factor, G-TSF, BSC-1 cell growth inhibitor, Polyergin, Cetermin). It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. There are two named isoforms of this protein, created by alternative splicing of the same gene (i.e., TGFB2).

Further reading

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000092969 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039239 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.