List of adverse effects of trazodone
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This is a list of adverse effects of the antidepressant trazodone, sorted by frequency of occurrence.[1][2][3]
Very common
Very common (>10% incidence) adverse effects include:
Common
Common (1–10% incidence) adverse effects include:
- Vomiting
- Constipation
- Diarrhea
- Backache
- Confusion
- Insomnia
- Dream disorder
- Disorientation
- Incoordination
- Nasal congestion
- Orthostatic hypotension
- Syncope
- Tremor
- Weight change
- Anxiety
- Hypotension
- Oedema
- Lack of coordination
- Dysgeusia
- Memory impairment
- Migraine
- Paraesthesia
- Agitation
- Dyspnoea
- Night sweats
Uncommon
Uncommon (0.1–1% incidence) adverse effects include:
- Hypersensitivity reaction
- Muscle twitching
- Amnesia
- Aphasia
- Hypoesthesia
- Speech disorder
- Bladder pain
- Urinary incontinence
- Gait disturbance
- Reflux oesophagitis
- Dry eye
- Eye pain
- Photophobia
- Hypoacusis
- Tinnitus
- Vertigo
- Acne
- Hyperhidrosis
- Photosensitivity reaction
- Flushing
Rare
Rare (<0.1%) adverse effects include:
- Urinary retention
- Prolonged QT interval
- Torsades de Pointes
- Ataxia
- Breast enlargement or engorgement
- Lactation
- Cardiospasm
- Stroke
- Chills
- Cholestasis
- Clitorism
- Congestive heart failure
- Diplopia
- Extrapyramidal symptoms
- Hallucinations
- Haemolytic anaemia
- Hirsutism
- Hyperbilirubinaemia
- Increased amylase
- Increased salivation
- Leukocytosis
- Leukonychia
- Jaundice
- Liver enzyme alterations
- Methemoglobinemia
- Paraesthesia
- Paranoid reaction
- Stupor
- Rash
- Seizure
- Priapism
- Pruritus
- Psoriasis
- Psychosis
- Suicidal ideation
- Suicidal behaviour
- Syndrome of inappropriate antidiuretic hormone secretion
- Tardive dyskinesia
- Serotonin syndrome
- Unexplained death
- Urticaria
- Vasodilation
References
- ↑ Truven Health Analytics, Inc. DrugPoint® System (Internet) [cited 2013 Oct 1]. Greenwood Village, CO: Thomsen Healthcare; 2013.
- ↑ OLEPTRO (trazodone hydrochloride) tablet, extended release OLEPTRO (trazodone hydrochloride) tablet, extended release [Angelini Pharma Inc.] [Internet]. DailyMed. 2013 [cited 2013 Oct 1]. Available from: http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=88c45123-f475-4dd0-bbac-c261868924ef Archived 2014-02-19 at the Wayback Machine
- ↑ trazodone (Rx) -Desyrel, Desyrel Dividose [Internet]. Medscape Reference. [cited 2013 Oct 1]. Available from:http://reference.medscape.com/drug/oleptro-trazodone-d-342965 Archived 2020-08-20 at the Wayback Machine