Somatrem
Jump to navigation
Jump to search
This article needs additional citations for verification. (June 2019) |
Clinical data | |
---|---|
Trade names | Protropin |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
ATC code | |
Identifiers | |
CAS Number | |
DrugBank | |
ChemSpider |
|
UNII | |
KEGG | |
ChEMBL | |
Chemical and physical data | |
Formula | C995H1537N263O301S8 |
Molar mass | 22256.26 g·mol−1 |
(what is this?) (verify) |
Somatrem, sold under the brand name Protropin, is an analogue of growth hormone (GH).[1]
Overview
Somatrem is a recombinant human growth hormone used for the treatment of short stature due to decreased or absent secretion of endogenous growth hormone.
Somatrem was first marketed under the brand name Protropin by Genentech in 1985.[2] It differs from endogenous growth hormone by the addition of an extra methionine at the N-terminus[3][circular reference].
Somatrem has largely been replaced by somatropin, marketed by several companies including by Genentech as the brand Nutropin.
References
- ^ Flodh H (1987). "Present situation worldwide regarding the use and clinical experience of Somatonorm (somatrem)". Acta Paediatrica Scandinavica. Supplement. 331: 1–4. doi:10.1111/j.1651-2227.1987.tb17089.x. PMID 3300150. S2CID 20410776.
- ^ "Genentech: Press Releases - Friday, Oct 18, 1985". www.gene.com.
- ^ Growth hormone therapy#cite note-32
External links
- "Somatrem". Drug Information Portal.
- HyperGH 14x Growth Hormone Info.
Categories:
- Articles with short description
- Short description matches Wikidata
- Articles needing additional references from June 2019
- All articles needing additional references
- Articles with changed CASNo identifier
- Chemicals that do not have a ChemSpider ID assigned
- Articles with changed EBI identifier
- Infobox drug articles without a structure image
- Articles without InChI source
- Drugs with no legal status
- Drugboxes which contain changes to verified fields
- Drugboxes which contain changes to watched fields
- All articles lacking reliable references
- Articles lacking reliable references from May 2019
- Peptides
- Growth hormones
- Drugs developed by Hoffmann-La Roche
- Drugs developed by Genentech
- All stub articles
- Systemic hormonal preparation stubs