List of adverse effects of venlafaxine

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The following list shows the rates of adverse symptoms seen in people taking venlafaxine.[1][2][3]

Very common (>10% incidence)

  • Headache — an often transient side effect that is common to most serotonin reuptake inhibitors and that most often occurs at the beginning of therapy or after a dose escalation.
  • Nausea — an adverse effect that is more common with venlafaxine than with the SSRIs. Usually transient and less severe in those receiving the extended release formulations.
  • Insomnia
  • Asthenia (weakness)
  • Dizziness
  • Ejaculation disorder — sexual side effects can be seen with virtually any antidepressant, especially those that inhibit the reuptake of serotonin (including venlafaxine).[4]
  • Somnolence
  • Dry mouth
  • Sweating
  • Withdrawal

Common (1–10% incidence)

Uncommon (0.1-1% incidence)

Rare (0.01–0.1% incidence)

Very rare (<0.01% incidence)


  1. "APO-VENLAFAXINE XR CAPSULES" (PDF). TGA eBusiness Services. Macquarie Park, NSW: Apotex Pty Ltd. 13 April 2012. Archived from the original on 19 April 2018. Retrieved 6 November 2013.
  2. "VENLAFAXINE (venlafaxine hydrochloride) tablet [Aurobindo Pharma Limited]". DailyMed. Aurobindo Pharma Limited. February 2013. Archived from the original on 30 January 2020. Retrieved 6 November 2013.
  3. "Effexor, Effexor XR (venlafaxine) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Archived from the original on 19 December 2013. Retrieved 6 November 2013.
  4. David Taylor; Carol Paton; Shitij Kapur, eds. (2012). The Maudsley Prescribing Guidelines in Psychiatry (illustrated ed.). John Wiley & Sons. ISBN 978-0-470-97948-8.