List of pigmentation changes

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Pigmentation changes in skin may be normal or a sign of skin disease.[1][2] Pigmentation disorders generally involve an abnormal pigmentation of skin, or underproduction or overproduction of melanin.[1]

Normal variant

Name Description Image
Pigmentary demarcation lines[1] Pigmentary demarcation lines1.png

Pigmentation disorders

Types Subtypes
Abnormal pigmentation Hemosiderin hyperpigmentation
Medication pigment
Postinflammatory pigmentation Postinflammatory pigmentation (DermNet NZ colour-hyperpig2).jpg
Idiopathic guttate hypomelanosis Porcelain-white patch extending peripherally (DermNet NZ guttate-hypomelanosis-2).jpg
Melasma Melasma2.jpg
Reticulate pigment disorders of the skin Dyschromatosis symmetrica hereditaria PMC3312656 IJD-57-42-g001.png
Dyschromatosis universalis hereditaria PMC4427145 cde-0007-0051-g02.png
Dowling–Degos disease Dowling-Degos disease (DermNet NZ colour-w-dowling-degos-1).jpg
Galli-Galli disease
Reticulate acropigmentation of Kitamura Reticulate acropigmentation of Kitamura (back of hands).png
Dermatopathia pigmentosa reticularis PMC4966426 IJD-61-468c-g002.png
Transient neonatal pustular melanosis Transient neonatal pustular melanosis (DermNet NZ neonatal-pustular-melanosis-v3).jpg
Leucoderma syphiliticum
Peutz-Jeghers syndrome
Metallic discolorations Arsenical keratosis Arsenic Poisoning.jpg
Titanium metallic discoloration
Chemical leukoderma
Vogt-Koyanagi-Harada syndrome Vitiligo (DermNet NZ vogt-koyanagi-harada-03).jpg
Alezzandrini syndrome Poliosis (DermNet NZ hair-nails-sweat-poliosis3).jpg
Vitiligo Vitiligo2.JPG
Congenital disorders of hypopigmentation[3]
Oculocutaneous albinism

See also


  1. 1.0 1.1 1.2 James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "36. Disturbances of pigmentation". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. pp. 862–880. ISBN 978-0-323-54753-6. Archived from the original on 2023-03-30. Retrieved 2023-06-03.
  2. Nicolaidou, Electra; Dessinioti, Clio; Katsambas, Andreas (2019). Hypopigmentation. CRC Press. ISBN 978-1-351-37962-5. Archived from the original on 2023-07-01. Retrieved 2022-08-26.
  3. Dessinioti, Clio; Stratigos, Alexander J.; Rigopoulos, Dimitris; Katsambas, Andreas D. (September 2009). "A review of genetic disorders of hypopigmentation: lessons learned from the biology of melanocytes". Experimental Dermatology. 18 (9): 741–749. doi:10.1111/j.1600-0625.2009.00896.x. ISSN 1600-0625. Archived from the original on 2022-08-02. Retrieved 2023-04-16.