List of WHO AWaRe antibiotics for common infections in hospital

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This is a list of antibiotics for common infections in hospital as detailed in the WHO AWaRe classification in the World Health Organization's book The WHO AWaRe (Access, Watch, Reserve) antibiotic book (2022).

Common infections in hospital
Infection Symptom Management Advice Image Notes AWaRe guidance (adults) AWaRe guidance (children)
Sepsis [1][2] Amikacin[1] Ampicillin[2]

or

Benzylpenicillin[2]


Ceftriaxone

or

Cefotaxime

Cefotaxime[2]

or

Ceftriaxone[2]

combined with

Gentamicin[1]

or

Cloxacillin[2]

Bacterial meningitis[3] First choice:

Cefotaxime[3]

or

Ceftriaxone[3]

Second line

Amoxicillin[3]

or

Ampicillin[3]

or

Benzylpenicillin[3]

or

Chloramphenicol[3]

Severe community acquired pneumonia[4]
Hospital acquired pneumonia[5]
Acute cholecystitis and cholangitis[6]
Pyogenic liver abscess[7]
Acute appendicitis[8]
Acute diverticulitis[9]
Clostridium difficile infection[10] Abdominal pain, fever, diarrhoea[10] Metronidazole[10]
Vancomycin
Upper urinary tract infection[11]
Acute bacterial osteomyelitis[12]
Septic arthritis[13]
Necrotising fasciitis[14]
Pyomyositis[15]
Febrile neutropenia[16]
Surgical prevention[17]

References

  1. 1.0 1.1 1.2 The WHO AWaRe, pp. 295-318
  2. 2.0 2.1 2.2 2.3 2.4 2.5 The WHO AWaRe, pp. 319-344
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 The WHO AWaRe, pp. 345-361
  4. The WHO AWaRe, pp. 362-380
  5. The WHO AWaRe, pp. 381-395
  6. The WHO AWaRe, pp. 396-413
  7. The WHO AWaRe, pp. 414-433
  8. The WHO AWaRe, pp. 434-453
  9. The WHO AWaRe, pp. 454-463
  10. 10.0 10.1 10.2 The WHO AWaRe. pp. 464-473
  11. The WHO AWaRe, pp. 474-488
  12. The WHO AWaRe, pp. 489-506
  13. The WHO AWaRe, pp. 507-522
  14. The WHO AWaRe, pp. 523-534
  15. The WHO AWaRe, pp. 535-544
  16. The WHO AWaRe, pp. 545-561
  17. The WHO AWaRe, pp. 562-574

Bibliography

  • The WHO AWaRe (Access, Watch, Reserve) antibiotic book. World Health Organization. 2022. Archived from the original on 13 August 2023. Retrieved 4 December 2023.