|Other names: Acid indigestion, pyrosis, cardialgia, acid regurgitation|
|Symptoms||Burning in the chest|
|Risk factors||Overweight, pregnancy, certain foods, certain medications, exposure to cigarette smoke|
|Medication||Antacids, proton pump inhibitor|
Heartburn, also known as acid indigestion, is a burning sensation in the central chest or upper central abdomen. The discomfort may feel like it rises from the upper central abdomen to the throat. There may also be a sour taste in your throat. It is a primary symptom of gastroesophageal reflux disease (GERD).
Heartburn is due to stomach acid entering the esophagus. Risk factors include being overweight, pregnancy, certain foods, certain medications, hiatus hernia, and exposure to cigarette smoke. Foods that are implicated include coffee, tomatoes, alcohol, and chocolate. Commonly involve medications include NSAIDs. Other conditions that may appear similar include angina.
Useful lifestyle changes include eating smaller meals, not eating before bedtime, losing weight if overweight, and raising the head of the bed. Medications that may help include an antacids or proton pump inhibitor. If these measures are not effective or other concerning symptoms are present a gastroscopy may be useful to rule out other causes. Heartburn affects more than 20% of the population in the US.
The terms indigestion includes heartburn along with a number of other symptoms. Indigestion is sometimes defined as a combination of epigastric pain and heartburn. Heartburn is commonly used interchangeably with gastroesophageal reflux disease rather than just to describe a symptom of burning in one's chest.
Because of the dangers inherent in an overlooked diagnosis of heart attack, cardiac disease should be considered first in people with unexplained chest pain. Further medical investigation, such as imaging, is often necessary.
Symptoms of heartburn can be confused with the pain that is a symptom of an acute myocardial infarction (heart attack) or angina. A description of burning or indigestion-like pain increases the risk of acute coronary syndrome, but not to a statistically significant level. In a group of people presenting to a hospital with GERD symptoms, 0.6% may be due to ischemic heart disease.
As many as 30% of chest pain patients undergoing cardiac catheterization have findings which do not account for their chest discomfort, and are often defined as having "atypical chest pain" or chest pain of undetermined origin. According to data recorded in several studies based on ambulatory pH and pressure monitoring, it is estimated that 25% to 50% of these patients have evidence of abnormal GERD.
Functional heartburn is heartburn of unknown cause. It is associated with other functional gastrointestinal disorders like irritable bowel syndrome and is the primary cause of lack of improvement post treatment with proton pump inhibitors (PPIs). PPIs are however still the primary treatment with response rates in about 50% of people. The diagnosis is one of elimination, based upon the Rome III criteria: 1) burning retrosternal discomfort; 2) elimination of heart attack and GERD as the cause; and 3) no esophageal motility disorders. It was found to be present in 22.3% of Canadians in one survey.
Heartburn can be caused by several conditions and a preliminary diagnosis of GERD is based on additional signs and symptoms. The chest pain caused by GERD has a distinct 'burning' sensation, occurs after eating or at night, and worsens when a person lies down or bends over. It also is common in pregnant women, and may be triggered by consuming food in large quantities, or specific foods containing certain spices, high fat content, or high acid content. If the chest pain is suspected to be heartburn, patients may undergo an upper GI series to confirm the presence of acid reflux. Heartburn or chest pain after eating or drinking and combined with difficulty swallowing may indicate esophageal spasms.
Relief of symptoms 5 to 10 minutes after the administration of viscous lidocaine and an antacid increases the suspicion that the pain is esophageal in origin. This however does not rule out a potential cardiac cause as 10% of cases of discomfort due to cardiac causes are improved with antacids.
Esophageal pH monitoring: a probe can be placed via the nose into the esophagus to record the level of acidity in the lower esophagus. Because some degree of variation in acidity is normal, and small reflux events are relatively common, esophageal pH monitoring can be used to document reflux in real-time.
Endoscopy: the oesophageal mucosa can be visualized directly by passing a thin, lighted tube with a tiny camera known as an endoscope attached through the mouth to examine the oesophagus and stomach. In this way, evidence of esophageal inflammation can be detected, and biopsies taken if necessary. Since an endoscopy allows a doctor to visually inspect the upper digestive tract the procedure may help identify any additional damage to the tract that may not have been detected otherwise.
Antacids such as calcium carbonate are often taken to treat the immediate problem, with further treatments depending on the underlying cause. Medicines such as H2 receptor antagonists or proton pump inhibitors are effective for gastritis and GERD, the two most common causes of heartburn. Antibiotics are used if H. pylori is present.
About 42% of the United States population has had heartburn at some point.
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