Primary cutaneous amyloidosis

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Primary cutaneous amyloidosis
Other names: Primary localized cutaneous amyloidosis[1]
Macular amyloidosis, located on the right lumbar region of the back

Primary cutaneous amyloidosis is a form of amyloidosis associated with oncostatin M receptor.[2][3] This type of amyloidosis has been divided into the following types:[4]: 520 

  • Macular amyloidosis is a cutaneous condition characterized by itchy, brown, rippled macules usually located on the interscapular region of the back.[4]: 521  Combined cases of lichen and macular amyloidosis are termed biphasic amyloidosis, and provide support to the theory that these two variants of amyloidosis exist on the same disease spectrum.[5]
  • Lichen amyloidosis is a cutaneous condition characterized by the appearance of occasionally itchy lichenoid papules, typically appearing bilaterally on the shins.[4]: 521 
  • Nodular amyloidosis is a rare cutaneous condition characterized by nodules that involve the acral a type of amyloidosis in skin.[6]
Nodular amyloidosis

See also


  1. "Primary cutaneous amyloidosis | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". Archived from the original on 18 April 2019. Retrieved 18 April 2019.
  2. "Amyloid". Archived from the original on 2019-02-17. Retrieved 2021-04-17.
  3. Arita K, South AP, Hans-Filho G, et al. (January 2008). "Oncostatin M receptor-beta mutations underlie familial primary localized cutaneous amyloidosis". Am. J. Hum. Genet. 82 (1): 73–80. doi:10.1016/j.ajhg.2007.09.002. PMC 2253984. PMID 18179886.
  4. 4.0 4.1 4.2 James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.
  5. Lichen amyloidosis of the auricular concha Archived 2010-04-23 at the Wayback Machine Craig, E. (2006) Dermatology Online Journal 12 (5): 1, University of California, Davis Department of Dermatology
  6. Johnstone, Ronald B. (2017). "14. Cutaneous deposits". Weedon's Skin Pathology Essentials (2nd ed.). Elsevier. p. 286. ISBN 978-0-7020-6830-0. Archived from the original on 2021-05-25. Retrieved 2022-09-27.

External links