Organomegaly

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Organomegaly is the abnormal enlargement of organs. For example, cardiomegaly is enlargement of the heart. Visceromegaly is the enlargement of abdominal organs.[1] Examples of visceromegaly are enlarged liver (hepatomegaly), spleen (splenomegaly), stomach, kidneys, and pancreas.

Definitions for various organs

Values refer to adults unless otherwise specified.

Organ Term for enlargement Cutoff for definition
Abdominal aorta Ectasia or mild dilation

>2.0 cm and <3.0 cm[2]

Abdominal aortic aneurysm
  • Moderate AAA: 3.0–5.0 cm[2]
  • Large or severe AAA: >5.0[2] or 5.5.[3] cm
Common bile duct Dilatation
  • Mild dilatation:[4] 8–12 mm
  • Moderate dilatation:[4] 12–16 mm
  • Severe dilatation:[4] 16–20 mm
  • Extremely severe dilatation:[4] >20 mm
Gallbladder Wall thickening 3 mm wall thickness[5]
Hydrops Greater than 5 cm transverse dimension[6]
Heart Cardiomegaly
Large intestine Dilation

Upper limit of normal range of diameter:[9]

Wall thickening Wall thickness 5 mm[10]
Kidneys Enlargement
Sex Upper limit of standard reference range
Right kidney Left kidney
Men[12] 160 g (5.6 oz) 175 g (6.2 oz)
Women[13] 175 g (6.2 oz) 190 g (6.7 oz)
Liver Hepatomegaly
Lymph nodes Lymphadenopathy Generally 10 mm[15][16]
Renal pelvis Part of hydronephrosis grading 4 – 20 mm:
  • Fetal: Anteroposterior diameter of less than 4 mm in fetuses up to 32 weeks of gestational age and 7 mm afterwards.[17]
  • Adults: cutoff values defined differently by different sources, with anteroposterior diameters ranging between 10 and 20 mm.[18] About 13% of normal healthy adults have a transverse pelvic diameter of over 10 mm.[19]
Prostate Prostatomegaly Volume over 30 cm3.
Pulmonary artery Dilation >29 mm[20]
Small intestine Dilation
  • Mild: 2.5–2.9 cm[23]
  • Moderate: 3-4 cm[23]
  • Severe: >4 cm[23]
Wall thickening 3–5 mm[26]
Spleen Splenomegaly
  • Moderate splenomegaly: the largest dimension is between 11–20 cm[27]
  • Severe splenomegaly: the largest dimension is greater than 20 cm[27]
  • Autopsy: Weight over upper limit of standard reference range, of 230 g (8.1 oz)[12][13]
Thoracic aorta Dilation Diameters:
  • >3.5 cm generally[30]

Upper limits of standard reference range:

  • 3.3 cm in small young individuals[31]
  • 4.3 cm among large elderly individuals.[31]
  • 2.3 cm among small young individuals[31]
  • 3.2 cm among large elderly individuals.[31]
Thoracic aortic aneurysm Diameter:
  • > 4.5 cm (US)[30]
  • > 4.0 cm (Korea)[32]
Testis Enlargement 5 cm (long axis) x 3 cm (short axis)[33]
Tonsil Enlarged tonsil 2.5 cm in length, 2.0 cm in width and 1.2 cm in thickness.[34]
Ureter Megaureter 6[35] or 7[36] mm
Urinary bladder Wall thickening 3–5 mm thick, and < 3 mm when well distended.[37]

References

  1. ^ "Visceromegaly on Medline Plus". Retrieved 6 February 2013.
  2. ^ a b c Page 56 in: Philip Lumb (2014). Critical Care Ultrasound E-Book. Elsevier Health Sciences. ISBN 9780323278171.
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  4. ^ a b c d Yunfu Lv, Wan Yee Lau, Haiying Wu, Shunwu Chang, NingLiu, Yejuan Li, Jie Deng (2015). "Etiological Causes of Intrahepatic and Extrahepatic Bile Duct Dilatation" (PDF). International Journal of New Technology and Research (IJNTR). 1 (8).{{cite journal}}: CS1 maint: multiple names: authors list (link)
  5. ^ van Breda Vriesman, Adriaan C.; Engelbrecht, Marc R.; Smithuis, Robin H. M.; Puylaert, Julien B. C. M. (2007). "Diffuse Gallbladder Wall Thickening: Differential Diagnosis". American Journal of Roentgenology. 188 (2): 495–501. doi:10.2214/AJR.05.1712. ISSN 0361-803X. PMID 17242260.
  6. ^ Page 256 in Neil Kaplowitz (1996). Liver and Biliary Diseases. Williams & Wilkins. ISBN 9780683045451.
  7. ^ Justin, M; Zaman, S; Sanders, J.; Crook, A. M; Feder, G.; Shipley, M.; Timmis, A.; Hemingway, H. (2007). "Cardiothoracic ratio within the "normal" range independently predicts mortality in patients undergoing coronary angiography". Heart. 93 (4): 491–494. doi:10.1136/hrt.2006.101238. ISSN 1355-6037. PMC 1861494. PMID 17164481.
  8. ^ Tracy, Richard Everett (2011). "Association of Cardiomegaly with Coronary Artery Histopathology and its Relationship to Atheroma". Journal of Atherosclerosis and Thrombosis. 18 (1): 32–41. doi:10.5551/jat.5090. ISSN 1880-3873. PMID 20953090.
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