Finrozole

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Finrozole
Names
Preferred IUPAC name
4-[(1R,2S)-3-(4-Fluorophenyl)-2-hydroxy-1-(1H-1,2,4-triazol-1-yl)propyl]benzonitrile
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.219.051 Edit this at Wikidata
UNII
  • InChI=1S/C18H15FN4O/c19-16-7-3-13(4-8-16)9-17(24)18(23-12-21-11-22-23)15-5-1-14(10-20)2-6-15/h1-8,11-12,17-18,24H,9H2/t17-,18+/m0/s1
    Key: SLJZVZKQYSKYNV-ZWKOTPCHSA-N
  • C1=CC(=CC=C1C[C@@H]([C@@H](C2=CC=C(C=C2)C#N)N3C=NC=N3)O)F
Properties
C18H15FN4O
Molar mass 322.343 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Finrozole is an aromatase (CYP19A1) inhibitor.[1]

References

  1. ^ Huuskonen, P; Myllynen, P; Storvik, M; Pasanen, M (2013). "The effects of aflatoxin B1 on transporters and steroid metabolizing enzymes in JEG-3 cells". Toxicology Letters. 218 (3): 200–6. doi:10.1016/j.toxlet.2013.01.015. PMID 23402939.


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