Sodium ferric gluconate

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Sodium ferric gluconate
Names
Trade namesFerrlecit
Other namesSodium ferric gluconate complex
Clinical data
Drug classIron supplement[1]
Main usesIron deficiency anemia in people on hemodialysis who are receiving epoetin[2]
Side effectsNausea, diarrhea, dizziness, shortness of breath, chest pain, leg cramps, pain[2]
Pregnancy
category
  • US: B (No risk in non-human studies)[3]
Routes of
use
Intravenous (IV)
Typical dose125 mg[1]
External links
AHFS/Drugs.comMonograph
MedlinePlusa614030
Legal
License data
Legal status
Chemical and physical data
FormulaC66H121Fe2NaO65
Molar mass2089.309 g·mol−1
3D model (JSmol)
  • O[C@H]([C@@H](O)C(O[Na])=O)[C@H](O)[C@H](O)CO.O[C@H]([C@@H](O)C(O1)=O)[C@H](O)[C@H](O)CO.[Fe]1(OC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)OC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
  • InChI=1S/5C12H22O11.C6H12O7.2Fe.Na.3O/c5*13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12;7-1-2(8)3(9)4(10)5(11)6(12)13;;;;;;/h5*4-11,13-20H,1-3H2;2-5,7-11H,1H2,(H,12,13);;;;;;/q;;;;;;2*+3;+1;3*-2/p-1/t5*4-,5-,6-,7-,8+,9-,10+,11-,12+;2-,3-,4+,5-;;;;;;/m111111....../s1
  • Key:MQBDAEHWGRMADS-XNHLMZCASA-M

Sodium ferric gluconate, sold under the brand name Ferrlecit, is a medication use to treat iron deficiency anemia in people on hemodialysis who are receiving epoetin therapy.[2] It is given by injection into a vein.[2] In this group intravenous iron has been found to be better than iron by mouth.[1]

Common side effects in adults include nausea, diarrhea, dizziness, shortness of breath, chest pain, leg cramps, and pain.[2] In children the most common side effects are headache, fast heart rate, and vomiting.[2] Other side effects may include low blood pressure and allergic reactions.[2] It is a type of iron supplement.[1]

Sodium ferric gluconate was approved for medical use in the United States in 1999.[2] In the United States it costs about 68 USD per dose as of 2021.[4] It is also available in Europe.[5]

Medical use

Dosage

It may be given as a 125 mg dose in adults or as 1.5 mg/kg in children.[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 "Sodium Ferric Gluconate Monograph for Professionals". Drugs.com. Retrieved 12 October 2021.
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 "Ferrlecit- sodium ferric gluconate complex injection". DailyMed. 25 September 2019. Retrieved 2 April 2020.
  3. "Sodium ferric gluconate complex Use During Pregnancy". Drugs.com. 16 December 2019. Retrieved 2 April 2020.
  4. "Ferrlecit Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 12 October 2021.
  5. "Intravenous iron-containing medicinal products". Retrieved 12 October 2021.

External links

Identifiers: