|Polyembryoma of the ovary, H&E stain|
|Symptoms||Lump in the tummy, early puberty, irregular menstrual cycle, pain|
|Usual onset||Teenagers, young adults|
Polyembryoma is a very aggressive form of germ cell tumor in the ovaries of females and testis of males, typically in teenagers and young adults. It may present with a lump in the tummy, early puberty, or irregular menstrual cycle. Some have pain.
Why it occurs is not well understood. Polyembryoma has features of both yolk sac tumour and undifferentiated teratoma/embryonal carcinoma, with a characteristic finding of embryoid bodies lying in a loose mesenchymal stroma.
- "Polyembryoma - About the Disease - Genetic and Rare Diseases Information Center". rarediseases.info.nih.gov. Archived from the original on 23 November 2021. Retrieved 7 July 2022.
- Beresford L, Fernandez CV, Cummings E, Sanderson S, Ming-Yu W, Giacomantonio M (April 2003). "Mediastinal polyembryoma associated with Klinefelter syndrome". Journal of Pediatric Hematology/Oncology. 25 (4): 321–323. doi:10.1097/00043426-200304000-00011. PMID 12679648.