Talk:Encephalitis/Archive 1

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Free image available

There's a set of free CT images here (under creative commons). I just don't have time to upload them right now. If you'd like to upload them but don't know how, I can help, drop me a note. delldot talk 19:32, 7 August 2008 (UTC)

Dubious claims

I just removed claims that millions died in the epidemic from 1917 to 1928. Based on a report in the Journal of the Royal Society of Medicine the number was likely in the thousands (and perhaps tens of thousands). Free access of reference here: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1296535/pdf/jrsocmed00036-0049.pdf . 23:57, 13 February 2010 (UTC)

Interesting

I spent two weeks in the hospital for viral encephalitis, dont remember anything and apparently should have died. i still don't understand what happened to me. david what! (talk) 23:24, 7 October 2011 (UTC)

Confusion

I don't think many people will confuse 'syphilis' with 'encephalitis'. So, why don't we just remove the 'not to be confused with syphilis' link? Netha Hussain (talk) 20:33, 31 January 2012 (UTC)

Including Encephalitis Global Inc. in the "External Links" section

Wishing to discuss: " 02:03, 27 August 2012‎ Yobol (talk | contribs)‎ . . (10,506 bytes) (-65)‎ . . (Undid revision 509297360 by Wendystation (talk)instead of reverting, please discuss on talk page why it should be included, after reviewing WP:EL) (undo)"

Encephalitis Global is an information resource for people seeking information in layman terms.

Wendy Station, President and webmaster of Encephalitis Global, Inc. was a guest to testify to Congress in Washington DC as an authority on the topic of encephalitis. (http://olpa.od.nih.gov/hearings/108/session2/reports/westnile.asp)

Encephalitis Global Inc. (http://www.encephalitisglobal.org) is a USA registered charity which qualifies for inclusion for the same reasons that the link to The Encephalitis Society (www.encephalitis.info) a UK registered charity, is included.

Encephalitis Global Inc. offers the only existing daily active encephalitis discussion forum available to the public.

Wendystation (talk) 23:41, 28 August 2012 (UTC)

Disagree. This site fails WP:ELNO criteria #1, and mention of discussion forum is prohibited by #10. I have removed the encephalitis society link as well; we are not here to promote specific charities. Yobol (talk) 02:35, 29 August 2012 (UTC)

Fair enough; I understand your statements. But... I do think that when society searches for more information on the topic of encephalitis, they would benefit to find Encephalitis Global, Inc. Perhaps I'm not fully understanding the purpose of each topic within Wikipedia. Nevertheless, I respect your decision... thank you. Wendystation (talk) 05:54, 29 August 2012 (UTC)

Prognosis?

Is encephalitis fatal? What proportion of affected individuals die? What proportion would die without treatment? What kinds of long-terms problems (if any) can it cause in survivors? Inclusion of this basic information would improve this article. (I know nothing on this topic, or else I would add the info myself.) 98.213.180.238 (talk) 02:48, 5 September 2012 (UTC)

LESS common in the tropics? Really?

"The incidence of acute encephalitis in Western countries is 7.4 cases per 100,000 population per year. In tropical countries, the incidence is 6.34 per 100,000 per year." Is this really the case - or a mistake? And if it IS the case, then why? (The reader shouldn't have to doubt whether it is a mistake or not, so then provide at least one reason to why this is the case.) — Preceding unsigned comment added by 221.146.196.18 (talk) 13:08, 11 March 2015 (UTC)

Proposed external link

Request to have a link to The Encephalitis Society added with the external link section of this Article. The Encephalitis Society is the International charity that prides support for all affected either directly or indirectly by Encephalitis and is regularly seen as the first contact. It also has shown to provide research and studies into Encephalitis and is also recognised for this. Links: The Encephalitis Society pwoolfy (talk) 21:04, 20 February 2017 (UTC)

, please see WP EL[1]--Ozzie10aaaa (talk) 21:41, 20 February 2017 (UTC)


note

Hello, we are a group of medical students editing this page as part of our class assignment. We have compiled a list of suggestions to improve this article and would appreciate community feedback before we proceed with these edits. Here is a list of our suggestions:

COMMENT: Overkill to have a separate subsection for each of your proposed changes. David notMD (talk) 19:34, 4 November 2017 (UTC)
What are you referring to User:David notMD? Doc James (talk · contribs · email) 00:58, 7 November 2017 (UTC)
Well, the students numbered their intended changes, and then there was added three = before and three = after the same numbers. I thought that unnecessary. David notMD (talk) 02:39, 7 November 2017 (UTC)

1

1. We propose to add this addition to the Encephalitis#epidemiology section: "The incidence of Encephalitis has not changed much over time, with an incidence of encephalitis in the US of 250,000 over the last 10 years. Approximately seven per 100,000 patients were hospitalized for encephalitis in the US during this time.

This note should be added to the epidemiology section, as it adds to the overall picture of the epidemiology of encephalitis.

Which last "10 years"? Better to give exact dates. Doc James (talk · contribs · email)

In response to User: Doc James we propose to change the edit to:

"The incidence of Encephalitis has not changed much over time, with an incidence of encephalitis in the US of 250,000 from 2005 to 2015. Approximately seven per 100,000 patients were hospitalized for encephalitis in the US during this time. [1]

2

2. We propose to add this addition to the encephalitis#treatment section: "Identification of poor prognostic factors include thrombocytopenia, cerebral edema, status epilepticus, and thrombocytopenia. In contrast, a normal encephalogram at the early stages of diagnosis is associated with high rates of survival."[1]

The addition of the prognosis of the disease is important to the article, because there is no information surrounding prognosis in the article thus far.

Sounds good Doc James (talk · contribs · email) 05:30, 4 November 2017 (UTC)

3

3. We propose to add this addition to the encephalitis#cause section, under autoimmune encephalitis: "There are two groups of autoimmune pathophysiology, consisting of classic paraneoplastic disorders to intracellular antigens, and autoantibodies to extracellular epitopes of ion channels, and receptors. The antigens and mechanisms of several forms of autoimmune encephalitis, such as lupus cerebritis and acute disseminated encephalomyelitis are not well established. [2]" 16vg11 (talk) 19:25, 3 November 2017 (UTC)

COMMENT: Learn the method of using the same ref more than once. With what you have, Ventatesan will show up twice, each with its own number. For #3, your text is in a too-medical style. Think of the potential audience as an educated person without medical training. Also, for Lancaster, consider a citation that goes to PubMed rather than directly to the journal. Here is a reference maker: https://tools.wmflabs.org/citation-template-filling/cgi-bin/index.cgi Enter the PMID number and it generates the reference. David notMD (talk) 21:38, 3 November 2017 (UTC)
Agree we need to figure out how to write that in easier to understand English. Doc James (talk · contribs · email) 05:30, 4 November 2017 (UTC)
Thank you for your comments and help with referencing. We would like to revise the addition as per your suggestion: "There are two groups of autoimmune pathophysiology.[2] The first group consists of classic paraneoplastic disorders, which occur due to cancer elsewhere in the body.[2] This type of encephalitis is related to intracellular antigens.[2] The second group is characterized by autoantibodies to cell-surface antigens.[2] The antigens and mechanisms of several forms of autoimmune encephalitis such as lupus cerebritis and acute disseminated encephalomyelitis are not well established.[2]" 16vg11 (talk) 16:00, 10 November 2017 (UTC)
Can you please insert your references in this? Please include a reference after every sentence, even if it is the same citation used multiple times. I think you should hold off on adding this one until we get some more feedback.JenOttawa (talk) 03:05, 15 November 2017 (UTC)

4

4. We propose the following change to the encephalitis#diagnosis section: "Polymerase chain reaction (PCR) testing of the cerebrospinal fluid, to detect the presence of viral DNA which is a sign of viral encephalitis.[3]"

  • it would help(in addition to) the reference[3] NHS which is currently present, so I would agree w/ adding it[4] and therefore making a stronger statement w/ the text you've indicated...IMO--Ozzie10aaaa (talk) 00:21, 4 November 2017 (UTC)
In response to User:Ozzie10aaaa: Can you please clarify what revision you would like for this edit? - nvm we misinterpreted what you were saying. Thank you for the positive feedback, we will add this edit to the page soon!
ok, your doing very good--Ozzie10aaaa (talk) 16:17, 15 November 2017 (UTC)

5

5. We propose the following change to the encephalitis#diagnosis section: "People should only be diagnosed with encephalitis if they have a decreased or altered level of consciousness, lethargy, or personality change for at least twenty-four hours without any other explainable cause.[4]"

Looks good. Doc James (talk · contribs · email) 05:30, 4 November 2017 (UTC)

6

6. We propose the following change to the encephalitis#cause section: "The majority of viral cases of encephalitis have an unknown cause, however the most common identifiable cause of viral encephalitis is from herpes simplex infection.[5]

  • a)you need to indicate the page #...b) you need to link[5]--Ozzie10aaaa (talk) 20:41, 6 November

@Ozzie10aaaa: citation has been updated to include link/reference online textbook (page number not included since source is online)

I therefore agree with the source--Ozzie10aaaa (talk) 16:19, 15 November 2017 (UTC)

7

7. We propose the following change to the encephalitis#treatment section: Add "Pyrimethamine-based maintenance therapy is often used to treat Toxoplasmic Encephalitis (TE), which is caused by Toxoplasma gondii and can be life-threatening for people with weak immune systems.[6] The use of highly active antiretroviral therapy (HAART), in conjunction with the established pyrimethamine-based maintenance therapy, decreases the chance of relapse in patients with HIV and TE from approximately 18% to 11%.[6] This is a significant difference as relapse may impact the severity and prognosis of disease and result in an increase in healthcare expenditure.[6]"

  • redid reference as it did not appear below (in prior edit[6])...the reference is good, why do you feel(objectively) the text needs it[7]?--Ozzie10aaaa (talk) 15:33, 7 November 2017 (UTC)
In response to User:Ozzie10aaaa: We believe that relapse and its relation to certain treatment approaches is an important aspect to consider. The text, as it stands, fails to mention any relapse rates. So, comparing a more commonly used maintenance therapy to a combined treatment that also utilizes antiretroviral therapy provides information on an effective treatment regimen, while addressing the risk of relapse. Sharm399 (talk) 17:37, 10 November 2017 (UTC)
good answer, I agree--Ozzie10aaaa (talk) 19:44, 10 November 2017 (UTC)

COMMENT: Small stuff - As of 11/8, ref 1 and 2 are the same, and 3 and 4 are the same. The first Lancaster links to the journal (wrong); the second Lancaster links to PubMed (right). Ross needs ISBN number and page numbers. Which Ozzie10aaaa already wrote. The last ref, looks like you trapped a sentence in between the beginning of the ref (the <ref name) and the body of the ref. David notMD (talk) 22:04, 8 November 2017 (UTC)

You fixed most of this, but refs 1 & 2 still duplicates David notMD (talk) 21:20, 10 November 2017 (UTC)

"::Thank you all for the feedback and suggestions! As of 11/13/2017 I believe we have made all the suggested changes but please let us know if there is something that we missed. FYI we will be adding our edits to the article on 11/15/2017.2001:1970:5223:8200:2CC9:6703:B92C:6118 (talk)" —Preceding undated comment added 02:41, 14 November 2017 (UTC)

Please be sure to login to Wikipedia when commenting or editing! A few of your citations need work #4,6 comments may not be addressed yet. Great work so far.JenOttawa (talk) 03:09, 15 November 2017 (UTC)
well done[9]--Ozzie10aaaa (talk) 13:44, 20 December 2017 (UTC)

ref

References

  1. ^ a b Venkatesan, A (June 2015). "Epidemiology and outcomes of acute encephalitis". Current opinion in neurology. 28 (3): 277–82. doi:10.1097/WCO.0000000000000199. PMID 25887770.
  2. ^ a b c d e f Lancaster E (2016). "The Diagnosis and Treatment of Autoimmune Encephalitis". J Clin Neurol. 12 (1): 1–13. doi:10.3988/jcn.2016.12.1.1. PMC 4712273. PMID 26754777.
  3. ^ Kneen R, Michael BD, Menson E, Mehta B, Easton A, Hemingway C, Klapper PE, Vincent A, Lim M, Carrol E, Solomon T (2012). "Management of suspected viral encephalitis in children - Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group national guidelines". J. Infect. 64 (5): 449–77. doi:10.1016/j.jinf.2011.11.013. PMID 22120594.
  4. ^ Venkatesan, A; Tunkel, AR; Bloch, KC; Lauring, AS; Sejvar, J; Bitnun, A; Stahl, JP; Mailles, A; Drebot, M; Rupprecht, CE; Yoder, J; Cope, JR; Wilson, MR; Whitley, RJ; Sullivan, J; Granerod, J; Jones, C; Eastwood, K; Ward, KN; Durrheim, DN; Solbrig, MV; Guo-Dong, L; Glaser, CA; International Encephalitis, Consortium. (October 2013). "Case definitions, diagnostic algorithms, and priorities in encephalitis: consensus statement of the international encephalitis consortium". Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 57 (8): 1114–28. doi:10.1093/cid/cit458. PMID 23861361.
  5. ^ Roos, Karen L.; Tyler, Kenneth L. (2015). "Meningitis, Encephalitis, Brain Abscess, and Empyema". Harrison's Principles of Internal Medicine (19 ed.). New York, NY: McGraw-Hill Education. ISBN 9780071802154.
  6. ^ a b c Connolly MP, Goodwin E, Schey C, Zummo J (2017). "Toxoplasmic encephalitis relapse rates with pyrimethamine-based therapy: systematic review and meta-analysis". Pathogens and global health. 111 (1): 31–44. doi:10.1080/20477724.2016.1273597. PMID 28090819.

The frequency appears to be based on a misinterpretation of the cited source; AFAICT, the number given is the source's estimate of the number of people who, at some point in 2015, were living with long-term (> 3 months) sequelae of encephalitis (or possibly the number of person-years lived with such sequelae; I'm not sure), not the number of people who developed encephalitis in 2015 (incidence), nor the number of people who were living with current encephalitis in 2015 (prevalence). 2600:8807:C180:1234:5DD1:6731:3938:E015 (talk) 20:51, 10 April 2019 (UTC)

will take a look--Ozzie10aaaa (talk) 13:00, 24 September 2019 (UTC)
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