User talk:Doc James

User talk:Doc James/Archive 1

Dientamoebiasis

Doc James, per [1] ...I find that "Dientamoeba Fragilis Infection Clinical Presentation: History, Physical, Causes". emedicine.medscape.com. Retrieved 3 July 2023. and Calderaro, Adriana; Buttrini, Mirko; Montecchini, Sara; Rossi, Sabina; Farina, Benedetta; Arcangeletti, Maria Cristina; De Conto, Flora; Chezzi, Carlo (12 February 2022). "Prevalence of Intestinal Parasitoses in a Non-Endemic Setting during a 10-Year Period (2011–2020): A Focus on Dientamoeba fragilis". Microorganisms. 10 (2): 426. doi:10.3390/microorganisms10020426. Retrieved 3 July 2023. indicates... weakness, pruritus, urticaria and per [2] indicates the initially mentioned edit/image is correct (as it is included, first image top left)?--Ozzie10aaaa (talk) 16:59, 3 July 2023 (UTC)

Ref says "On the other hand, few cases of pruritus and urticaria in patients harbouring D. fragilis have been reported over the years" And I am not seeing it mentioned here https://pubmed.ncbi.nlm.nih.gov/30165915/ Also not mentioned here https://www.cdc.gov/dpdx/dientamoeba/index.html Doc James (talk · contribs · email) 17:55, 3 July 2023 (UTC)

User:Ozzie10aaaa It does mention it here https://www.ncbi.nlm.nih.gov/pmc/articles/PMC452553/ but not as a main symptoms. We mention it in the text, I am just concerns an image of hives gives this rare symptoms undue weight... Your thought? Doc James (talk · contribs · email) 17:56, 3 July 2023 (UTC)

(original ref/top[3]).. Interestingly, other clinical signs such as eosinophilia, pruritus, anal pruritus, and urticaria have also been reported in association with dientamoebiasis...however per 'undue weight' your correct, Ozzie--Ozzie10aaaa (talk) 18:23, 3 July 2023 (UTC)

Diarrheal diseases/Clostridioides difficile infection

Doc James, while [4] does not indicate but how many are from C dif?, I believe per [5] Diarrheal diseases are a group of illnesses that are usually caused by viral, bacterial, or protist infections. They tend to be spreadthrough contaminated food or drinking water, or between people through the fecal-oral route or direct contact ...is indicating 'generally' not 'individually', Ozzie--Ozzie10aaaa (talk) 23:06, 11 July 2023 (UTC)

Agree this is deaths from all causes of diarrhea so belongs at the diarrhea page. It is not specific for C. dif and thus does not really fit there. Doc James (talk · contribs · email) 23:17, 11 July 2023 (UTC)

actually that wasn't the point I was trying to make, but (from a certain point of view)...ok--Ozzie10aaaa (talk) 23:55, 11 July 2023 (UTC)

I would imagine only a tiny fracture of people who die from diarrhea due so from C diff. Doc James (talk · contribs · email) 05:27, 12 July 2023 (UTC)

smaller than other better known pathogens (E. coli and so on) but not 'tiny' per:

• Alexandridou, Maria; Cattaert, Tom; Verstraeten, Thomas (April 2021). "Estimation of Risk of Death Attributable to Acute Gastroenteritis Not Caused by Clostridioides difficile Infection Among Hospitalized Adults in England". Clinical Epidemiology. Volume 13: 309–315. doi:10.2147/CLEP.S296516. PMID 33935520. Retrieved 12 July 2023. {{cite journal}}: |volume= has extra text (help)
• Czepiel, Jacek; Krutova, Marcela; Mizrahi, Assaf; Khanafer, Nagham; Enoch, David A.; Patyi, Márta; Deptuła, Aleksander; Agodi, Antonella; Nuvials, Xavier; Pituch, Hanna; Wójcik-Bugajska, Małgorzata; Filipczak-Bryniarska, Iwona; Brzozowski, Bartosz; Krzanowski, Marcin; Konturek, Katarzyna; Fedewicz, Marcin; Michalak, Mateusz; Monpierre, Lorra; Vanhems, Philippe; Gouliouris, Theodore; Jurczyszyn, Artur; Goldman-Mazur, Sarah; Wultańska, Dorota; Kuijper, Ed J.; Skupień, Jan; Biesiada, Grażyna; Garlicki, Aleksander (13 March 2021). "Mortality Following Clostridioides difficile Infection in Europe: A Retrospective Multicenter Case-Control Study". Antibiotics (Basel, Switzerland). 10 (3): 299. doi:10.3390/antibiotics10030299. ISSN 2079-6382. Retrieved 12 July 2023.
• Balsells, Evelyn; Shi, Ting; Leese, Callum; Lyell, Iona; Burrows, John; Wiuff, Camilla; Campbell, Harry; Kyaw, Moe H.; Nair, Harish (June 2019). "Global burden of Clostridium difficile infections: a systematic review and meta-analysis". Journal of Global Health. 9 (1): 010407. doi:10.7189/jogh.09.010407. ISSN 2047-2986.

--Ozzie10aaaa (talk) 14:23, 12 July 2023 (UTC)

This is a good source https://pubmed.ncbi.nlm.nih.gov/30603078/ but doesn't mention deaths. Doc James (talk · contribs · email) 14:36, 12 July 2023 (UTC)

• from the article[6] itself about 453,000 cases occurred in the United States in 2011, resulting in 29,000 deaths An additional review indicates 30,000 for 2023.

• now this is U.S. only (I have not looked up South America, Asia, Africa, Australia (and perhaps a better source(s) than the ones I indicated for Europe though from the second journal from the top A total of 624 patients were included, of which 415 were deceased (cases) and 209 were still alive 90 days after a CDI diagnosis (controls) (A Retrospective Multicenter Case-Control Study), Ill probably have more time on the week end to look for sources to these continents/regions--Ozzie10aaaa (talk) 18:32, 12 July 2023 (UTC)

Great lets add that to the article as it is specific to the topic in question :-) Doc James (talk · contribs · email) 19:28, 12 July 2023 (UTC)

• updated U.S.-30,000--Ozzie10aaaa (talk) 22:33, 12 July 2023 (UTC)
• Europe- this indicates 7,864 fatal HA CDI cases European Centre for Disease Prevention and Control --Ozzie10aaaa (talk) 22:53, 12 July 2023 (UTC)
• Africa- was unable to locate a reliable source/statistics, like a good review ( see)--Ozzie10aaaa (talk) 22:53, 12 July 2023 (UTC)
• South America-paywalled--Ozzie10aaaa (talk) 23:13, 12 July 2023 (UTC)
• Asia-pacific low mortality...The molecular epidemiology of C. difficile strains identified in this study may contribute to the apparent milder outcomes of CDI in the region. A predominance of more virulent strains may be associated with more severe disease outcomes in North American and European countries, e.g. the prevalent RTs 027 and 078. In Europe, RTs 056 and 018 have caused severe or complicated infection--Ozzie10aaaa (talk) 23:19, 12 July 2023 (UTC)

Thanks Doc James (talk · contribs · email) 23:27, 12 July 2023 (UTC)

crop

Doc James, I cropped this [7] however I still get this (which has the caption in the image)[8], thank you for your help, Ozzie

User:Ozzie10aaaa often just takes a bit of time to update. How does it look now? Doc James (talk · contribs · email) 00:23, 25 July 2023 (UTC)

Doc James, it looks perfect, thank you. Ozzie--Ozzie10aaaa (talk) 01:42, 25 July 2023 (UTC)

• Doc James, short day will be back tomorrow, Ozzie--Ozzie10aaaa (talk) 22:31, 29 July 2023 (UTC) (BTW, I was trying to place double image infobox here I don't really know how to this fix lua error on the template to do so, so for the time being I placed second image in 'map' (infobox),Ozzie)

User:Ozzie10aaaa Not sure what is not working? I removed an unneeded tag. Doc James (talk · contribs · email) 15:59, 2 August 2023 (UTC)

actually, my mistake (they use the term map but its really image2 per here) thank you, Ozzie--Ozzie10aaaa (talk) 18:30, 2 August 2023 (UTC)

OWID

Doc James, (I know your away ) when you have chance Influenza treatment seems to be having an issue w/ OWID?, thanks, Ozzie--Ozzie10aaaa (talk) 18:16, 30 August 2023 (UTC)(BTW , hectic day today, will be back tomorrow, Ozzie)

Not seeing it on this list here https://owidm.wmcloud.org/ User:Ozzie10aaaa so it might not be in the mirror yet. You can ask Tim about adding it.Doc James (talk · contribs · email) 15:22, 5 September 2023 (UTC)

ok([9]),Ozzie--Ozzie10aaaa (talk) 12:38, 6 September 2023 (UTC)

And if you do not hear from him we can email Tim. Doc James (talk · contribs · email) 16:06, 6 September 2023 (UTC)

Doc James, sounds good, Ozzie--Ozzie10aaaa (talk) 18:16, 6 September 2023 (UTC)

He will be back end of Sept Doc James (talk · contribs · email) 03:19, 7 September 2023 (UTC)

BA.2.86

Doc James, (from [10]) I went thru BA.2.86, and added some recent material... per Mahase, Elisabeth (13 September 2023). "Covid-19: New "Pirola" variant BA.2.86 continues to spread in UK and US". BMJ. 382: 2097. doi:10.1136/bmj.p2097. ISSN 1756-1833. Retrieved 14 September 2023. and Geddes, Linda. "Everything you need to know about the new BA.2.86 "Pirola" variant | Gavi, the Vaccine Alliance". www.gavi.org. Retrieved 14 September 2023. I don't think its anything that will take us back a couple of years,IMO (though I will keep an eye on it)

in terms of Variants of SARS-CoV-2 (on second thought) yes it may be best to simply turn back on mirroring from EN WP,--Ozzie10aaaa (talk) 21:20, 14 September 2023 (UTC)

Mirroring restored :-) Doc James (talk · contribs · email) 23:47, 14 September 2023 (UTC)

thank you, Ozzie--Ozzie10aaaa (talk) 14:42, 15 September 2023 (UTC)

• Doc James, short day today, will be back tomorrow,Ozzie--Ozzie10aaaa (talk) 22:40, 23 September 2023 (UTC)(BTW you indicated to place all except NC and ND to commons, however for Familial episodic pain syndrome a video 'MP4' is not allowed to upload at commons, it is 'Attribution 4.0 International (CC BY 4.0)', Ozzie--Ozzie10aaaa (talk) 21:10, 24 September 2023 (UTC))

User:Ozzie10aaaa So you can convert it with an online video converter to WebM or you can upload to NC Commons Doc James (talk · contribs · email) 08:06, 25 September 2023 (UTC)

ok, Ozzie--Ozzie10aaaa (talk) 13:32, 25 September 2023 (UTC)

• Doc James, thank you for this edit [11] it was there when I forked it [12], however Infection is rather large (now~ 160,000) I should have been more thorough in looking at prior refs, Ozzie--Ozzie10aaaa (talk) 13:28, 27 September 2023 (UTC)

OWID2

(BTW, in terms of this [13] I think I found another OWID w/ an issue Glucose tolerance test, Ozzie)

The list of OWID items is here[14] Corrected that one. Did the one here ever work?Influenza treatment Is there a functional version elsewhere on the net? Doc James (talk · contribs · email) 02:25, 1 October 2023 (UTC)

Doc James, thanks for fixing  :-) ...no the 'Influenza treatment' has not worked (I'm not certain if there may be a version elsewhere that does work), I'll just switch it with something else,Ozzie--Ozzie10aaaa (talk) 19:17, 1 October 2023 (UTC)

Do we have enough changes to this article Influenza treatment to keep it forked? Generally we should be making fairly significant updates / changes to forked articles. Expecially with this being an fully open image.[15] Best Doc James (talk · contribs · email) 04:41, 2 October 2023 (UTC)

good point , I'll deal with this article next[16],Ozzie--Ozzie10aaaa (talk) 15:32, 2 October 2023 (UTC)

• Doc James short day today, will be back tomorrow, Ozzie--Ozzie10aaaa (talk) 22:50, 18 October 2023 (UTC)(BTW 1 FBXW7 neurodevelopmental syndrome seems rather new not alot on it [diagnosis,treatment?], and.... 2 this [17] indicates [18] however the foot of the image indicates Reprinted by permission from Springer Nature: Springer Nature, Drugs, Inotersen: first global approval, Keam SJ, 2018;78(13):1371–1376 I haven't uploaded an image with this wording before?, Ozzie)

User:Ozzie10aaaa I think that means it is fully copyrighted. Doc James (talk · contribs · email) 23:19, 22 October 2023 (UTC)

deleted thanks, Ozzie--Ozzie10aaaa (talk) 12:47, 23 October 2023 (UTC)

Research Enquiry: Claims about 'warm water' treatment for prostate issues.

Hi,

Recently amongst the various ads on YouTube, I saw one advertising a presentation on a site called "Landmark-Health" (The URL being linked to - https://landmark-health.com/ffmax1?cmc_adid=ga_678548247491_20715466681.), I'm of course exceptionaly skeptical about medical claims made in advertising on Social media sites, especially given that the linked page, doesn't of itself link directly to specific journal sources such as Pubmed or The Lancet.

If there were simple pharmacological cures for prostate issues, then I would have expected to have heard more about this through mainstream media.

I appreciate that the focus of your efforts on MDWiki are not debunking, but do you have volunteers here willing to do literature review to assess the veracity of social media claims? ShakespeareFan00 (talk) 16:09, 27 October 2023 (UTC)

User:ShakespeareFan00 reading that link makes me cringe. It is up to those who believe something works to prove it does. And if the benefits are as large as the promoters claim, only a relatively small trial would be required. It is picking up small benefits that require large trials. We are more trying to provide an overview of healthcare, not so much debunk potential myths that are out there. Doc James (talk · contribs · email) 05:08, 28 October 2023 (UTC)

comment

• Doc James I dont know how you did this [19]... in the infobox (for that matter), but your a Genius, (I certainly have had my share of issues with OWID)--Ozzie10aaaa (talk) 13:25, 30 October 2023 (UTC)
  • User:Ozzie10aaaa No worries. Spent a lot of hours building this. The problem I still havn't figured out how to solve is to have some at 100% width like in the infobox and some at 50% width in the body of the article... Doc James (talk · contribs · email) 22:53, 30 October 2023 (UTC)

you want to change the percent width?...OMG,(BTW Happy Halloween 🎃) Ozzie--Ozzie10aaaa (talk) 23:42, 30 October 2023 (UTC)

• Doc James, hectic day will be back tomorrow (BTW I left [20]... seems interesting on PD), Ozzie--Ozzie10aaaa (talk) 17:46, 9 November 2023 (UTC)