Talk:Cold agglutinin disease

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note

isnt there an infectious disease that causes cold agglutination of blood sample below a certain temperature?

Both infectious mononucleosis and Mycoplasma pneumoniae are associated with post-infectious cold agglutinin disease, if that's what you're referring to. --David Iberri (talk) 17:28, 3 August 2008 (UTC)[reply]

Merge from Secondary_cold_agglutinin_syndrome

It is sugguested from user:Logophile59 in Talk:Secondary cold agglutinin syndrome#Candidate for merge/deletion--Wolfch (talk) 21:06, 3 May 2019 (UTC)[reply]

Below is his opinion

Although I spent some time working on this page, I have now realized that there is a pre-existing (better) page on Cold agglutinin disease that covers both primary and secondary CAD. I suggest that this page and another page written by the same user, Primary chronic cold agglutinin disease should be deleted or merged with the pre-existing page.

— user:Logophile59

--Wolfch (talk) 21:11, 3 May 2019 (UTC)[reply]

I think it is ok to merge Secondary_cold_agglutinin_syndrome to this article.--Wolfch (talk) 06:52, 6 May 2019 (UTC)[reply]

Merge from Primary chronic cold agglutinin disease

It is sugguested from user:Logophile59 in Talk:Primary chronic cold agglutinin disease#Duplicate of another (better) page--Wolfch (talk) 21:06, 3 May 2019 (UTC)[reply]

Below is his opinion

There is already a page on Cold agglutinin disease which contains sections on both primary and secondary CAD and covers all the material covered here. I suggest removing this page.

— user:Logophile59

--Wolfch (talk) 21:11, 3 May 2019 (UTC)[reply]

  • There is very little in the two pages I flagged for possible merge that isn't covered in this page. It might be worth transferring the figure and legend from Secondary cold agglutinin syndrome to further explain the role of the complement system. Otherwise, this page is far better than the other two. Logophile59 (talk) 12:42, 4 May 2019 (UTC)[reply]
  • I think maybe we can move there two articles to draft pages first and wait for expanding.--Wolfch (talk) 04:22, 6 May 2019 (UTC)[reply]
  • I think it is ok to merge Primary chronic cold agglutinin disease to this article because much information in it is for cold agglutinin disease (CAD) or Primary chronic cold agglutinin disease (Primary CAD,) not only for Primary chronic cold agglutinin disease.--Wolfch (talk) 06:55, 6 May 2019 (UTC)[reply]
  • I agree with Wolfch. These pages have almost nothing of value that isn't already in the Cold agglutinin disease page. There is no benefit to the proliferation of pages that say the same thing. Also, if you plan to expand these two articles with new, useful material, why wouldn't you expand this page instead? The two syndromes are the same, they only differ in the origins of the antibodies that cause disease. Logophile59 (talk) 01:26, 12 May 2019 (UTC)[reply]
    • Hey, thanks for the nice points! Maybe I am afraid of causing confusion between their types? (shown as follows) Anyway, I will expand these articles in this day or two and then we can decide where should these articles go. Best.

Classification

AIHA can be classified as warm autoimmune hemolytic anemia or cold autoimmune hemolytic anemia, which includes cold agglutinin disease and paroxysmal cold hemoglobinuria. These classifications are based on the characteristics of the autoantibodies involved in the pathogenesis of the disease. Each has a different underlying cause, management, and prognosis, making classification important when treating a patient with AIHA.[1].

Autoimmune hemolytic anemia
  • Idiopathic
  • Secondary
  • Acute, transient (Infections other than syphilis)[2]: 259 
  • Chronic (syphilis)[2]: 259 
  • Drug-induced immune hemolytic anemia [2]: 259 
  • Autoimmune type
  • Drug absorption type
  • Neoantigen type

[4]

References

  1. ^ Zanella, A.; Barcellini, W. (2014-09-30). "Treatment of autoimmune hemolytic anemias". Haematologica. 99 (10). Ferrata Storti Foundation (Haematologica): 1547–1554. doi:10.3324/haematol.2014.114561. ISSN 0390-6078. PMC 4181250. PMID 25271314.
  2. ^ a b c d e f g h "Concise review: Autoimmune Hemolytic Anemia". American Journal of Hematology. Wiley: 258-271. 2002.
  3. ^ Berentsen, Sigbjørn; Beiske, Klaus; Tjønnfjord, Geir E. (2007-07-21). "Primary chronic cold agglutinin disease: An update on pathogenesis, clinical features and therapy". Hematology (Amsterdam, Netherlands). 12 (5). Informa UK Limited: 361–370. doi:10.1080/10245330701445392. ISSN 1607-8454. PMC 2409172. PMID 17891600.
  4. ^ Berentsen, Sigbjørn; Sundic, Tatjana (2015-01-29). "Red Blood Cell Destruction in Autoimmune Hemolytic Anemia: Role of Complement and Potential New Targets for Therapy". BioMed Research International. 2015. Hindawi Limited. 363278-1–363278-11. doi:10.1155/2015/363278. ISSN 2314-6133. PMC 4326213. PMID 25705656.{{cite journal}}: CS1 maint: unflagged free DOI (link)

--It's gonna be awesome!✎Talk♬ 03:25, 12 May 2019 (UTC)[reply]

Dear Logophile59 and Wolfch, I find that I haven't been ready yet to expand the said articles since "within a day or two" which I said approximately two days ago from now. I am poor in time management, probably because I am a not-yet-optimally-treated ADHD 😝, therefore I don't want to set another exact date to expand them and will respect the consensus of you two and others on whether or not to merge the said articles at the moment despite I know I plan to expand them in the near future. Best. --It's gonna be awesome!✎Talk♬ 14:27, 13 May 2019 (UTC)[reply]
err, I just found there are still twelve hours to go until my promised deadline. But even so, it's unlikely that I will be able to expand those articles in the next 12 hours to the extent that you would feel it reasonable to give them standalone spaces. Hence, it's ok for you to decide at the moment. --It's gonna be awesome!✎Talk♬ 14:37, 13 May 2019 (UTC)[reply]
Thank for It's gonna be awesome's reply. I still think we need to merge Secondary cold agglutinin syndrome and Primary chronic cold agglutinin disease to this article.--Wolfch (talk) 14:56, 13 May 2019 (UTC)[reply]
I agree. I don't know how merging works though, so I hope Wolfch can enlighten us. Logophile59 (talk) 01:50, 14 May 2019 (UTC)[reply]
Sorry for the late reply. If we can decide which paragraphs in Primary_chronic_cold_agglutinin_disease and Secondary_cold_agglutinin_syndrome and are necessary to add to Cold_agglutinin_disease and which paragraphs are not. Maybe I can move these paragraphs.--Wolfch (talk) 15:10, 29 May 2019 (UTC)[reply]

Below are my opinions for Primary chronic cold agglutinin disease and Secondary cold agglutinin syndrome.

  • Primary chronic cold agglutinin disease
    • leading paragraphes: "Primary CAD is distinguished from secondary cold agglutinin syndrome by the absence of any underlying or associated disease" is ok for Primary cold agglutinin disease. it is ok to remove other sentences.
    • Classification: remove
    • Pathophysiology: I am not sure.
      • Red blood cell destruction: not for Primary chronic CAD only. remove
    • Management: not for Primary chronic CAD only. remove
    • Prognosis: not for Primary chronic CAD only. remove
  • Secondary_cold_agglutinin_syndrome
    • leading paragraphes: "It occurs when autoantibodies bind to red blood cells, rendering them subject to attack by the complement system.[2] It is similar to primary cold agglutinin disease (Primary CAD, CAD) but much less common." is ok for Secondary_cold_agglutinin_syndrome. it is ok to remove other sentences.
    • Classification: remove
    • Signs and symptoms: not for Secondary CAD only. remove
    • Etiology: not sure.
    • Pathophysiology: not sure
    • Management: removed.

--Wolfch (talk) 15:10, 29 May 2019 (UTC)[reply]

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