List of skin conditions associated with internal cancer

From WikiProjectMed
Jump to navigation Jump to search

This is a list of skin conditions associated with internal cancer.[1][2] It does not include skin infections associated with cancer or cancers that spread to skin.[2] Some have stronger associations with cancers than others.[3]

Cutaneous conditions associated with internal benign tumors and/or malignancies
Cutaneous condition Internal malignancy Image Notes
Acanthosis nigricans Gastric adenocarcinoma[3]
Acquired ichthyosis[4] Hodgkin disease, non-Hodgkin lymphoma, mycosis fungoides, multiple myeloma, carcinomatosis[4]
Acrokeratosis paraneoplastica Squamous cell carcinoma of the upper respiratory or gastrointestinal tracts[3] Purplish scaling of fingers, toes, nose, ears, with brittle nails.[3]
Clubbing of fingers[3] Lung cancer[3]
Dermatomyositis Lung cancer in men, breast and gynaecological tumours in women and colorectal cancers in both sexes
Dermatitis herpetiformis Lymphoma
Erythema gyratum repens[5] Lung cancer, breast cancer, oesophageal cancer[1]
Erythroderma and exfoliative dermatitis Mycosis fungoides or Sézary syndrome
Hypertrichosis lanuginosa acquisita Lung cancer
Leser–Trélat sign Gastrointestinal adenocarcinoma Sudden appearance of many itchy seborrheoic keratoses.[4]
Necrolytic migratory erythema Glucagon secreting pancreatic islet cell adenoma[3]
Nonmelanoma skin cancer
Paraneoplastic keratoderma
Paraneoplastic pemphigus Non-Hodgkin lymphoma, CLL, Castleman disease[4][nb 1]
Chronic lymphocytic leukemia
Castleman's disease[nb 1]
Sarcoma
Thymoma
Paraneoplastic pigmentation Small cell bronchial carcinoma
Pityriasis rotunda Hepatocellular carcinoma[1] May be one or upto 20.[1]
Porphyria cutanea tarda and variegate porphyrias Hepatocellular Carcinoma
Pyoderma gangrenosum Hematological malignancy
Scleroderma‐like skin changes Carcinoid syndrome
Sweet syndrome Hematological malignancy
Tripe palms[3] Lung cancer, stomach cancer, ovarian cancer[3]
Trousseau sign of malignancy Pancreatic cancer[4] Also known as migratory thrombophlebitis.[3]

Footnotes

  1. 1.0 1.1 Non-Hodgkin lymphoma is the most common cause of paraneoplastic pemphigus in adults. Castleman's disease is the most common cause of paraneoplastic pemphigus in children.

See also

References

  1. 1.0 1.1 1.2 1.3 James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "28. Dermal and subcutaneous tumors". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. pp. 633–634. ISBN 978-0-323-54753-6. Archived from the original on 2023-08-08. Retrieved 2023-08-07.
  2. 2.0 2.1 Wick, Mark R.; Patterson, James W. (July 2019). "Cutaneous paraneoplastic syndromes". Seminars in Diagnostic Pathology. 36 (4): 211–228. doi:10.1053/j.semdp.2019.01.001. ISSN 0740-2570. PMID 30736994. Archived from the original on 2022-11-21. Retrieved 2023-08-01.
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 3.9 Fonia, Athina; Baran, Robert (2021). "Cutaneous paraneoplastic syndromes with nail involvement". In Lipner, Shari (ed.). Nail Disorders: Diagnosis and Management, An Issue of Dermatologic Clinics. Elsevier. pp. 175–182. ISBN 978-0-323-70924-8. Archived from the original on 2023-08-02. Retrieved 2023-08-01.
  4. 4.0 4.1 4.2 4.3 4.4 James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "27. Genodermatoses and congenital anomalies". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. pp. 563–565. ISBN 978-0-323-54753-6. Archived from the original on 2023-08-05. Retrieved 2023-08-04.
  5. Bolognia, Jean L.; Schaffer, Julie V.; Duncan, Karynne O.; Ko, Christine (2021). "15. Figurate erythemas". Dermatology Essentials (2nd ed.). Elsevier. pp. 142–148. ISBN 978-0-323-70971-2. Archived from the original on 2023-08-08. Retrieved 2023-08-05.