Hexahydrocannabihexol

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Hexahydrocannabihexol
Identifiers
  • (6aR,10aR)-6,6,9-trimethyl-3-hexyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
Chemical and physical data
FormulaC22H34O2
Molar mass330.512 g·mol−1
3D model (JSmol)
  • CCCCCCc1cc2OC(C)(C)[C@@H]3CCC(C)C[C@H]3c2c(O)c1

Hexahydrocannabihexol (HHCH) is a semi-synthetic cannabinoid derivative. It was first synthesised by Roger Adams in 1942 and found to be more potent than either the pentyl or heptyl homologues, or the unsaturated tetrahydrocannabinol analogue.[1][2]

Legality

HHCH is classified as an "intoxicating cannabinoid" in Colorado and requires a license for its manufacture or distribution.[3]

In Japan, after several people who had eaten gummy candies containing HHCH fell ill, this chemical was officially added to the list of designated substances. And since 2 December 2023, it has been illegal to possess, use, or sell it.[4]

See also

References

  1. ^ Adams R, Loewe S, Smith CM, McPhee WD (March 1942). "Tetrahydrocannabinol homologs and analogs with marihuana activity. XIII". Journal of the American Chemical Society. 64 (3): 694–697. doi:10.1021/ja01255a061.
  2. ^ "Hexahydrocannabinol (HHC) and related substances" (PDF). European Monitoring Centre for Drugs and Drug Addiction. 2023.
  3. ^ "Senate Bill 23-271" (PDF). General Assembly, State of Colorado.
  4. ^ "Japanese government to ban cannabis-like substance, HHCH". NHK. 2023-11-21. Retrieved 2023-11-22.
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